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Product Details
MA1-25778
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Non-human primate
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4i51
Immunogen
Nuclear matrix extract from human MDCK cells.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
tissue culture supernatant with 30% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_795066
Product Specific Information
MA1-25778 will not react with mouse or rat.
Suggested positive controls for this product are HeLa nuclear extract/HeLa cells.
Target Information
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ45706; FLJ59041; nucl antibody; Nucleolin; Protein C23
Gene Aliases: C23; NCL
UniProt ID: (Human) P19338
Entrez Gene ID: (Human) 4691, (Dog) 608445
nucleotide binding
single-stranded DNA binding
RNA binding
calcium ion binding
protein binding
protein C-terminus binding
selenocysteine insertion sequence binding
rRNA primary transcript binding
telomeric DNA binding
histone binding
identical protein binding
laminin binding
poly(A) RNA binding
ErbB-4 class receptor binding
angiogenesis
endocytosis
spermatogenesis
positive regulation of tumor necrosis factor production
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
liver regeneration
positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
regulation of rRNA processing
positive regulation of interleukin-6 secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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