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Immunogen sequence: MNGRADFREP NAEVPRPIPH IGPDYIPTEE ERRVFAECND ESFWFRSVPL AATSMLITQG LISKGILSSH PKYGSIPKLI LACIMGYFAG KLSYVKTCQE KFKKLENSPL GEALRSGQAR RSSPPGHYYQ KSKYDSSVSG QSSFVTSPAA DNIEMLPHYE PIPFSSSMNE SAPTGITDHI VQGPDPNLEE SPKRKNITYE ELRNKNRESY EVSLTQKTDP SVRPMHERVP KKEVKVNKYG DTWDE
Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer (PubMed:20515946). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: expressed during mesenchymal induction 2; FLJ20455; induced during mesenchymal induction 2; MGC111072; OCIA domain-containing protein 1; Ovarian cancer immunoreactive antigen domain containing 1; Ovarian carcinoma immunoreactive antigen
Gene Aliases: 6030432N09Rik; AI481327; ASRIJ; AW557942; B230209J16Rik; BB021357; Emi2; Imi2; OCIA; OCIAD1; TPA018
UniProt ID: (Human) Q9NX40, (Rat) Q5XIG4, (Mouse) Q9CRD0
Entrez Gene ID: (Human) 54940, (Rat) 289590, (Mouse) 68095
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