Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MAALSCLLD SVRRDIKKVD RELRQLRCID EFSTRCLCDL YMHPYCCCDL HPYPYCLCYS KRSRSCGLCD LYPCCLCDYK LYCLRPSLRS LERKAIRAIE DEKRELAKLR RTTNRILASS CCSSNILGSV NVCGFEPDQV KVRVKDGKVC VSAERENRYD CLGSKKYSYM NICKEFSLPP CVDEKDVTYS YGLGSCVKIE SPCYPCTSPC SPCSPCNPCN PCSPCNPCSP YDPCNPCYPC GSRFSCRKMI L (1-250 aa encoded by BC104457)
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cancer/testis antigen 133; Heat shock protein beta-10; Heat shock protein family B member 10; HspB10; outer dense fiber of sperm tails, 27-kD; Outer dense fiber protein 1; outer dense fiber protein-1; Protein RT7; RTS 5/1; Sperm outer dense fiber major protein 1
Gene Aliases: CT133; HSPB10; ODF; ODF1; ODF2; ODF27; ODFP; ODFPG; ODFPGA; ODFPGB; RT7; SODF
UniProt ID: (Human) Q14990, (Rat) P21769
Entrez Gene ID: (Human) 4956, (Mouse) 18285, (Rat) 24610
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