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Product Details
PA5-21102
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 17 amino acid peptide near the center of human OGFOD2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11153421
Product Specific Information
A suggested positive control is 293 cell lysate.
PA5-21102 can be used with blocking peptide PEP-1216.
Target Information
OGFOD2 is a member of the 2-OG-Fe(II) dioxygenase family which plays an important role in ischemic survival and stress. Like the related protein OGFOD1, OGFOD2 is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. Little is known about the function of OGFOD2, but its similarity to OGFOD1 suggests that it is a novel stress granule component that may play an important proapoptotic role in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-oxoglutarate and iron-dependent oxygenase domain containing 2; 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2
Gene Aliases: 1300006G11Rik; 5730405M13Rik; AU041636; AW552395; OGFOD2; RGD1310594
UniProt ID: (Human) Q6N063, (Mouse) Q9CQ04
Entrez Gene ID: (Human) 79676, (Mouse) 66627, (Rat) 288657
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
L-ascorbic acid binding
dioxygenase activity
sulfonate dioxygenase activity
molecular_function
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
metal ion binding
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
RNA metabolism protein
Performance Guarantee
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