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Product Details
PA5-59138
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human OGFOD2. Recombinant protein control fragment (Product #RP-97691).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644966
Product Specific Information
Immunogen sequence: ARPEVYDSLQ DAALAPEFLA VTEYSVSPDA DLKGLLQRLE TVSEEKRIYR VPVFTAPFCQ ALLEELEHFE QSDMPKGRPN TMNNYG
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.
Target Information
OGFOD2 is a member of the 2-OG-Fe(II) dioxygenase family which plays an important role in ischemic survival and stress. Like the related protein OGFOD1, OGFOD2 is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. Little is known about the function of OGFOD2, but its similarity to OGFOD1 suggests that it is a novel stress granule component that may play an important proapoptotic role in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-oxoglutarate and iron-dependent oxygenase domain containing 2; 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2
Gene Aliases: 1300006G11Rik; 5730405M13Rik; AU041636; AW552395; OGFOD2; RGD1310594
UniProt ID: (Human) Q6N063, (Mouse) Q9CQ04
Entrez Gene ID: (Human) 79676, (Mouse) 66627, (Rat) 288657
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
L-ascorbic acid binding
dioxygenase activity
sulfonate dioxygenase activity
molecular_function
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
metal ion binding
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
RNA metabolism protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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