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Product Details
H00118427-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1F11
Immunogen
OLFM3 (NP_477518, 108 a.a. approximately 206 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: FRQIEDDRKT LMTKHFQELK EKMDELLPLI PVLEQYKTDA KLITQFKEEI RNLSAVLTGI QEEIGAYDYE ELHQRVLSLE TRLRDCMKKL TCGKLMKIT
Target Information
OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Noelin-3; olfactomedin related ER localized protein 3; Olfactomedin-3; Optimedin
Gene Aliases: NOE3; NOELIN3; OLFM3; OPTIMEDIN; UNQ1924/PRO4399
UniProt ID: (Human) Q6IMJ1
Entrez Gene ID: (Human) 118427
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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