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Recommended positive controls: A431, HeLa, HepG2, U87-MG, mouse brain, rat brain.
Predicted reactivity: Mouse (96%), Rat (97%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PABPC5 encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. PABPC5 is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PABP-5; poly A binding protein, cytoplasmic 5-like; poly(A) binding protein, cytoplasmic 5; Polyadenylate-binding protein 5
Gene Aliases: C820015E17; PABP5; PABPC5
UniProt ID: (Human) Q96DU9
Entrez Gene ID: (Human) 140886, (Mouse) 93728, (Rat) 688518
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