Product References
A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes.
EBioMedicine
Syed F,Singhal D,Raedschelders K,Krishnan P,Bone RN,McLaughlin MR,Van Eyk JE,Mirmira RG,Yang ML,Mamula MJ,Wu H,Liu X,Evans-Molina C
MA3-019 was used in Competition assay to identify a core set of modulated pathways across distinct mouse models of T1D and identified PDIA1 as a potential human biomarker of β cell stress in T1D.
Sun Jan 01 00:00:00 EST 2023
von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient-derived endothelial colony-forming cells.
Journal of thrombosis and haemostasis : JTH
Bowman M,Casey L,Selvam SN,Lima PDA,Rawley O,Hinds M,Tuttle A,Grabell J,Iorio A,Walker I,Lillicrap D,James P
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Fri Jul 01 00:00:00 EDT 2022
von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient-derived endothelial colony-forming cells.
Journal of thrombosis and haemostasis : JTH
Bowman M,Casey L,Selvam SN,Lima PDA,Rawley O,Hinds M,Tuttle A,Grabell J,Iorio A,Walker I,Lillicrap D,James P
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Fri Jul 01 00:00:00 EDT 2022
GGCX variants leading to biallelic deficiency to γ-carboxylate GRP cause skin laxity in VKCFD1 patients.
Human mutation
Ghosh S,Kraus K,Biswas A,Müller J,Forin F,Singer H,Höning K,Hornung V,Watzka M,Oldenburg J,Czogalla-Nitsche KJ
MA3-019 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot to understand the development of non-hemorrhagic phenotypes and hence improve treatment in VKCFD1 patients by genotype-phenotype analysis.
Sat Jan 01 00:00:00 EST 2022
Natural and Designed Proteins Inspired by Extremotolerant Organisms Can Form Condensates and Attenuate Apoptosis in Human Cells.
ACS synthetic biology
Veling MT,Nguyen DT,Thadani NN,Oster ME,Rollins NJ,Brock KP,Bethel NP,Lim S,Baker D,Way JC,Marks DS,Chang RL,Silver PA
MA3-019 was used in Immunocytochemistry-immunofluorescence to demonstrate that driving protective proteins into the condensate state increases apoptosis protection, and highlights the ability of DHR81 condensates to sequester caspase-7.
Fri Mar 18 00:00:00 EDT 2022
Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice.
Life science alliance
Li G,Li X,Yang L,Wang S,Dai Y,Fekry B,Veillon L,Tan L,Berdeaux R,Eckel-Mahan K,Lorenzi PL,Zhao Z,Lehner R,Sun K
MA3-019 was used in Western Blot to reveal that adipose tissue-specific Ces1d knock-out (FKO) mice gained more body weight with increased fat mass during a high fat-diet challenge.
Mon Aug 01 00:00:00 EDT 2022
Homodimerized cytoplasmic domain of PD-L1 regulates its complex glycosylation in living cells.
Communications biology
Zhou L,Chai F,He Y,Zhou Z,Guo S,Li P,Sun Q,Zu X,Liu X,Huang Q,Zhong Y,Zhou A,Wang X,Ren H
MA3-019 was used in Immunocytochemistry-immunoflourescence to demonstrate that PD-L1 forms homodimers in cells, and the homodimers play important roles in PD-L1 complex glycosylation and T-cell mediated toxicity.
Tue Aug 30 00:00:00 EDT 2022
Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.
The Journal of experimental medicine
Györfi AH,Matei AE,Fuchs M,Liang C,Rigau AR,Hong X,Zhu H,Luber M,Bergmann C,Dees C,Ludolph I,Horch RE,Distler O,Wang J,Bengsch B,Schett G,Kunz M,Distler JHW
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunohistochemistry
Mon Sep 06 00:00:00 EDT 2021
Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.
The Journal of experimental medicine
Györfi AH,Matei AE,Fuchs M,Liang C,Rigau AR,Hong X,Zhu H,Luber M,Bergmann C,Dees C,Ludolph I,Horch RE,Distler O,Wang J,Bengsch B,Schett G,Kunz M,Distler JHW
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunohistochemistry
Mon Sep 06 00:00:00 EDT 2021
Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.
The Journal of experimental medicine
Györfi AH,Matei AE,Fuchs M,Liang C,Rigau AR,Hong X,Zhu H,Luber M,Bergmann C,Dees C,Ludolph I,Horch RE,Distler O,Wang J,Bengsch B,Schett G,Kunz M,Distler JHW
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunohistochemistry
Mon Sep 06 00:00:00 EDT 2021
The Golgi-associated retrograde protein (GARP) complex plays an essential role in the maintenance of the Golgi glycosylation machinery.
Molecular biology of the cell
Khakurel A,Kudlyk T,Bonifacino JS,Lupashin VV
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Sun Aug 15 00:00:00 EDT 2021
Identification and Characterization of Human Norovirus NTPase Regions Required for Lipid Droplet Localization, Cellular Apoptosis, and Interaction with the Viral P22 Protein.
Microbiology spectrum
Yen JB,Chen LW,Wei LH,Hung CH,Wang SS,Lin CL,Chang PJ
MA3-019 was used in Immunocytochemistry to propose that the norovirus NTPase may utilize LDs or the ER as replication platforms to benefit viral replication and pathogenesis.
Fri Sep 03 00:00:00 EDT 2021
Identification and Characterization of Human Norovirus NTPase Regions Required for Lipid Droplet Localization, Cellular Apoptosis, and Interaction with the Viral P22 Protein.
Microbiology spectrum
Yen JB,Chen LW,Wei LH,Hung CH,Wang SS,Lin CL,Chang PJ
MA3-019 was used in Immunocytochemistry to propose that the norovirus NTPase may utilize LDs or the ER as replication platforms to benefit viral replication and pathogenesis.
Fri Sep 03 00:00:00 EDT 2021
Potential Dual Role of West Nile Virus NS2B in Orchestrating NS3 Enzymatic Activity in Viral Replication.
Viruses
Tseng AC,Nerurkar VR,Neupane KR,Kae H,Kaufusi PH
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Sun Jan 31 00:00:00 EST 2021
The c.863A>G (p.Glu288Gly) variant of the CTSD gene is not associated with CLN10 disease.
Molecular genetics & genomic medicine
Yang J,Ding X,Meng S,Cai J,Zhou W
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Fri Oct 01 00:00:00 EDT 2021
The c.863A>G (p.Glu288Gly) variant of the CTSD gene is not associated with CLN10 disease.
Molecular genetics & genomic medicine
Yang J,Ding X,Meng S,Cai J,Zhou W
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Fri Oct 01 00:00:00 EDT 2021
TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis.
The Journal of clinical investigation
Dees C,Pötter S,Zhang Y,Bergmann C,Zhou X,Luber M,Wohlfahrt T,Karouzakis E,Ramming A,Gelse K,Yoshimura A,Jaenisch R,Distler O,Schett G,Distler JH
MA3-019 was used in Immunohistochemistry to identify a pathway of epigenetic imprinting of fibroblasts in fibrotic disease with translational implications for the development of targeted therapies in fibrotic diseases.
Fri May 01 00:00:00 EDT 2020
Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication.
Antiviral research
Ma-Lauer Y,Zheng Y,Malešević M,von Brunn B,Fischer G,von Brunn A
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Wed Jan 01 00:00:00 EST 2020
Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication.
Antiviral research
Ma-Lauer Y,Zheng Y,Malešević M,von Brunn B,Fischer G,von Brunn A
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Wed Jan 01 00:00:00 EST 2020
Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells.
Frontiers in cell and developmental biology
Lin HH,Lo YL,Wang WC,Huang KY,I KY,Chang GW
MA3-019 was used in Immunocytochemistry-immunoflourescence to summarize that FAM46A is a novel poly(A) polymerase that functions as a critical intracellular modulator of hemoglobinization.
Mon Sep 28 00:00:00 EDT 2020
Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells.
Frontiers in cell and developmental biology
Lin HH,Lo YL,Wang WC,Huang KY,I KY,Chang GW
MA3-019 was used in Immunocytochemistry-immunoflourescence to summarize that FAM46A is a novel poly(A) polymerase that functions as a critical intracellular modulator of hemoglobinization.
Mon Sep 28 00:00:00 EDT 2020
Novel role of dynamin-related-protein 1 in dynamics of ER-lipid droplets in adipose tissue.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li X,Yang L,Mao Z,Pan X,Zhao Y,Gu X,Eckel-Mahan K,Zuo Z,Tong Q,Hartig SM,Cheng X,Du G,Moore DD,Bellen HJ,Sesaki H,Sun K
MA3-019 was used in Western Blotting to report that DRP1 translocates to endoplasmic reticulum (ER) in response to β-adrenergic stimulation.
Mon Jun 01 00:00:00 EDT 2020
Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension.
PloS one
Salibe-Filho W,Araujo TLS,G Melo E,B C T Coimbra L,Lapa MS,Acencio MMP,Freitas-Filho O,Capelozzi VL,Teixeira LR,Fernandes CJCS,Jatene FB,Laurindo FRM,Terra-Filho M
MA3-019 was used in Western Blotting to investigate the pathophysiological mechanisms underlying chronic thromboembolic pulmonary hypertension.
Mon Jan 18 00:00:00 EST 2021
Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension.
PloS one
Salibe-Filho W,Araujo TLS,G Melo E,B C T Coimbra L,Lapa MS,Acencio MMP,Freitas-Filho O,Capelozzi VL,Teixeira LR,Fernandes CJCS,Jatene FB,Laurindo FRM,Terra-Filho M
MA3-019 was used in Western Blotting to investigate the pathophysiological mechanisms underlying chronic thromboembolic pulmonary hypertension.
Mon Jan 18 00:00:00 EST 2021
TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.
eLife
Chen M,Amado N,Tan J,Reis A,Ge M,Abreu JG,He X
MA3-019 was used in Immunocytochemistry-immunoflourescence to identify, via CRISPR/Cas9 genome-wide loss-of function screening, an orphan five-pass transmembrane protein TMEM79 (also called MATTRIN), as a specific antagonist of Wnt signaling.
Mon Sep 14 00:00:00 EDT 2020
Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer.
The Journal of experimental medicine
Gao Q,Yang Z,Xu S,Li X,Yang X,Jin P,Liu Y,Zhou X,Zhang T,Gong C,Wei X,Liu D,Sun C,Chen G,Hu J,Meng L,Zhou J,Sawada K,Fruscio R,Grunt TW,Wischhusen J,Vargas-Hernández VM,Pothuri B,Coleman RL
MA3-019 was used in Immunofluorescence in immunohistochemistry on frozen tissues to study the aggressive nature of high-grade serous ovarian cancer ascitic tumour cells, which are prone to forming heterotypic spheroids with fibroblasts.
Mon Mar 04 00:00:00 EST 2019
Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress.
Cell death and differentiation
Bravo-Sagua R,Parra V,Ortiz-Sandoval C,Navarro-Marquez M,Rodríguez AE,Diaz-Valdivia N,Sanhueza C,Lopez-Crisosto C,Tahbaz N,Rothermel BA,Hill JA,Cifuentes M,Simmen T,Quest AFG,Lavandero S
Published figure using PDI monoclonal antibody (Product # MA3-019) in Western Blot
Mon Jul 01 00:00:00 EDT 2019
Redox Activation of Nox1 (NADPH Oxidase 1) Involves an Intermolecular Disulfide Bond Between Protein Disulfide Isomerase and p47phox in Vascular Smooth Muscle Cells.
Arteriosclerosis, thrombosis, and vascular biology
Gimenez M,Veríssimo-Filho S,Wittig I,Schickling BM,Hahner F,Schürmann C,Netto LES,Rosa JC,Brandes RP,Sartoretto S,De Lucca Camargo L,Abdulkader F,Miller FJ,Lopes LR
MA3-019 was used in Immunohistochemistry to investigate the molecular mechanism by which PDI (protein disulfide isomerase A1) activates Nox1 (NADPH oxidase) and the functional implications of PDI in Nox1 activation in vascular disease.
Fri Feb 01 00:00:00 EST 2019
Cell-surface HSP70 associates with thrombomodulin in endothelial cells.
Cell stress & chaperones
Araujo TLS,Venturini G,Moretti AIS,Tanaka LY,Pereira AC,Laurindo FRM
Published figure using PDI monoclonal antibody (Product # MA3-019) in Western Blot
Tue Jan 01 00:00:00 EST 2019
Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas.
Cell death & disease
De Bessa TC,Pagano A,Moretti AIS,Oliveira PVS,Mendonça SA,Kovacic H,Laurindo FRM
MA3-019 was used in Western Blotting to examine the mechanisms by which protein disulphide isomerases, including PDIA1, are implicated in cancer progression.
Wed Feb 13 00:00:00 EST 2019
Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas.
Cell death & disease
De Bessa TC,Pagano A,Moretti AIS,Oliveira PVS,Mendonça SA,Kovacic H,Laurindo FRM
MA3-019 was used in Western Blotting to examine the mechanisms by which protein disulphide isomerases, including PDIA1, are implicated in cancer progression.
Wed Feb 13 00:00:00 EST 2019
Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites.
Nature communications
Alenquer M,Vale-Costa S,Etibor TA,Ferreira F,Sousa AL,Amorim MJ
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Tue Apr 09 00:00:00 EDT 2019
Alzheimer Aβ Assemblies Accumulate in Excitatory Neurons upon Proteasome Inhibition and Kill Nearby NAKα3 Neurons by Secretion.
iScience
Komura H,Kakio S,Sasahara T,Arai Y,Takino N,Sato M,Satomura K,Ohnishi T,Nabeshima YI,Muramatsu SI,Kii I,Hoshi M
MA3-019 was used in Immunocytochemistry to study the location in neurons where amylospheroids form and how they reach their targets to induce neurodegeneration.
Fri Mar 29 00:00:00 EDT 2019
Subcellular Localization and Functional Characterization of GII.4 Norovirus-Encoded NTPase.
Journal of virology
Yen JB,Wei LH,Chen LW,Chen LY,Hung CH,Wang SS,Chang PJ
MA3-019 was used in Immunocytochemistry-immunoflourescence to show that the virus-encoded NTPase must have multiple activities during viral replication or pathogenesis.
Thu Mar 01 00:00:00 EST 2018
Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria.
Scientific reports
Lobet E,Willemart K,Ninane N,Demazy C,Sedzicki J,Lelubre C,De Bolle X,Renard P,Raes M,Dehio C,Letesson JJ,Arnould T
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Mon Mar 26 00:00:00 EDT 2018
StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis.
The Journal of biological chemistry
Fukushima M,Dasgupta D,Mauer AS,Kakazu E,Nakao K,Malhi H
MA3-019 was used in Immunocytochemistry-immunoflourescence to propose a model of how StAR-related lipid transfer domain 11 mediates ceramide trafficking in palmitate-treated cells and stimulates exosome biogenesis.
Fri Sep 28 00:00:00 EDT 2018
StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis.
The Journal of biological chemistry
Fukushima M,Dasgupta D,Mauer AS,Kakazu E,Nakao K,Malhi H
MA3-019 was used in Immunocytochemistry-immunoflourescence to propose a model of how StAR-related lipid transfer domain 11 mediates ceramide trafficking in palmitate-treated cells and stimulates exosome biogenesis.
Fri Sep 28 00:00:00 EDT 2018
Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway.
Frontiers in cellular neuroscience
Lambert L,Dubayle D,Fafouri A,Herzog E,Csaba Z,Dournaud P,El Mestikawy S,Bernard V
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Tue Sep 29 00:00:00 EDT 2020
Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway.
Frontiers in cellular neuroscience
Lambert L,Dubayle D,Fafouri A,Herzog E,Csaba Z,Dournaud P,El Mestikawy S,Bernard V
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Tue Sep 29 00:00:00 EDT 2020
Endoplasmic reticulum, Golgi, and lysosomes are disorganized in lung fibroblasts from chronic obstructive pulmonary disease patients.
Physiological reports
Weidner J,Jarenbäck L,Åberg I,Westergren-Thorsson G,Ankerst J,Bjermer L,Tufvesson E
MA3-019 was used in Immunocytochemistry-immunoflourescence to show that COPD patients have phenotypic changes in the lung fibroblasts endomembrane pathway, and respond differently to stress.
Thu Mar 01 00:00:00 EST 2018
Endoplasmic reticulum-resident protein 57 (ERp57) oxidatively inactivates human transglutaminase 2.
The Journal of biological chemistry
Yi MC,Melkonian AV,Ousey JA,Khosla C
MA3-019 was used in Immunocytochemistry-immunoflourescence to investigate switch 'off' mechanism of transglutaminase 2 (TG2).
Fri Feb 23 00:00:00 EST 2018
EMC3 coordinates surfactant protein and lipid homeostasis required for respiration.
The Journal of clinical investigation
Tang X,Snowball JM,Xu Y,Na CL,Weaver TE,Clair G,Kyle JE,Zink EM,Ansong C,Wei W,Huang M,Lin X,Whitsett JA
MA3-019 was used in Immunohistochemistry to demonstrate that EMC3 is required for murine pulmonary surfactant synthesis and lung function at birth.
Fri Dec 01 00:00:00 EST 2017
Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies.
Science signaling
Waters AM,Ozkan-Dagliyan I,Vaseva AV,Fer N,Strathern LA,Hobbs GA,Tessier-Cloutier B,Gillette WK,Bagni R,Whiteley GR,Hartley JL,McCormick F,Cox AD,Houghton PJ,Huntsman DG,Philips MR,Der CJ
MA3-019 was used in Immunocytochemistry-immunoflourescence to evaluate 22 commercially available anti-RAS antibodies with a set of distinct reagents and cell lines for their specificity and selectivity in recognising the intended RAS isoforms and mutants.
Tue Sep 26 00:00:00 EDT 2017
Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.
Antioxidants & redox signaling
Manuel AM,Walla MD,Faccenda A,Martin SL,Tanis RM,Piroli GG,Adam J,Kantor B,Mutus B,Townsend DM,Frizzell N
MA3-019 was used in Western Blotting to investigate whether succination alters PDI oxidoreductase activity, directly linking mitochondrial stress and endoplasmic reticulum stress.
Fri Dec 01 00:00:00 EST 2017
Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.
Antioxidants & redox signaling
Manuel AM,Walla MD,Faccenda A,Martin SL,Tanis RM,Piroli GG,Adam J,Kantor B,Mutus B,Townsend DM,Frizzell N
MA3-019 was used in Western Blotting to investigate whether succination alters PDI oxidoreductase activity, directly linking mitochondrial stress and endoplasmic reticulum stress.
Fri Dec 01 00:00:00 EST 2017
Embryonic lethal abnormal vision proteins and adenine and uridine-rich element mRNAs after global cerebral ischemia and reperfusion in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Wang H,Tri Anggraini F,Chen X,DeGracia DJ
MA3019 was used in western blot to study HuR, HuB, HuC, and HuD in hippocampal CA1 neurons
Sat Apr 01 00:00:00 EDT 2017
Vesicular acetylcholine transporter (VAChT) over-expression induces major modifications of striatal cholinergic interneuron morphology and function.
Journal of neurochemistry
Janickova H,Prado VF,Prado MAM,El Mestikawy S,Bernard V
MA3-019 was used in Immunohistochemistry to demonstrate that ChAT-ChR2 mice present major alterations of CIN neuronal morphology and increased behavioral sensitization to cocaine, supporting the notion that the increased levels of VAChT observed in these mice make them fundamentally different from wild-type mice.
Fri Sep 01 00:00:00 EDT 2017
Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families.
Scientific reports
Moretti AIS,Pavanelli JC,Nolasco P,Leisegang MS,Tanaka LY,Fernandes CG,Wosniak J,Kajihara D,Dias MH,Fernandes DC,Jo H,Tran NV,Ebersberger I,Brandes RP,Bonatto D,Laurindo FRM
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Fri Dec 08 00:00:00 EST 2017
HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway.
Nature communications
Yamashita Y,Anczurowski M,Nakatsugawa M,Tanaka M,Kagoya Y,Sinha A,Chamoto K,Ochi T,Guo T,Saso K,Butler MO,Minden MD,Kislinger T,Hirano N
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Wed May 10 00:00:00 EDT 2017
Peri/Epicellular Protein Disulfide Isomerase Sustains Vascular Lumen Caliber Through an Anticonstrictive Remodeling Effect.
Hypertension (Dallas, Tex. : 1979)
Tanaka LY,Araújo HA,Hironaka GK,Araujo TL,Takimura CK,Rodriguez AI,Casagrande AS,Gutierrez PS,Lemos-Neto PA,Laurindo FR
MA3-019 was used in Neutralization experiments to study the role of the cell surface pool of the endoplasmic reticulum redox chaperone protein disulfide isomerase-A1 on the regulation of disease associated vascular architecture.
Tue Mar 01 00:00:00 EST 2016
An ERp57-mediated disulphide exchange promotes the interaction between Burkholderia cenocepacia and epithelial respiratory cells.
Scientific reports
Pacello F,D'Orazio M,Battistoni A
MA3-019 was used in immunocytochemistry to identify ERp57 as a protein disulfide isomerase involved in the interaction between Burkholderia cenocepacia and epithelial cells
Tue Feb 16 00:00:00 EST 2016
Optogenetic control of organelle transport and positioning.
Nature
van Bergeijk P,Adrian M,Hoogenraad CC,Kapitein LC
MA3-019 was used in immunocytochemistry to establish a method of optical control of intracellular transport using light-sensitive heterodimerization to recruit specific cytoskeletal motor proteins to selected cargoes and test how local positioning of recycling endosomes contributes to axon
Thu Feb 05 00:00:00 EST 2015
Optogenetic acidification of synaptic vesicles and lysosomes.
Nature neuroscience
Rost BR,Schneider F,Grauel MK,Wozny C,Bentz C,Blessing A,Rosenmund T,Jentsch TJ,Schmitz D,Hegemann P,Rosenmund C
MA3-019 was used in immunocytochemistry to analyze synaptic vesicles and lysosomes and optogenetic acidification
Tue Dec 01 00:00:00 EST 2015
An analysis of critical factors for quantitative immunoblotting.
Science signaling
Janes KA
Published figure using PDI monoclonal antibody (Product # MA3-019) in Western Blot
Tue Apr 07 00:00:00 EDT 2015
Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells.
Journal of lipid research
Cheng D,Weckerle A,Yu Y,Ma L,Zhu X,Murea M,Freedman BI,Parks JS,Shelness GS
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Sat Aug 01 00:00:00 EDT 2015
Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells.
Journal of lipid research
Cheng D,Weckerle A,Yu Y,Ma L,Zhu X,Murea M,Freedman BI,Parks JS,Shelness GS
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Sat Aug 01 00:00:00 EDT 2015
Characterization of N-glycosylation sites on the extracellular domain of NOX1/NADPH oxidase.
Free radical biology & medicine
Matsumoto M,Katsuyama M,Iwata K,Ibi M,Zhang J,Zhu K,Nauseef WM,Yabe-Nishimura C
MA3-019 was used in immunocytochemistry to identify N-glycosylation sites on the NOX1 subunit of NADPH oxidase
Sat Mar 01 00:00:00 EST 2014
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
The Journal of cell biology
Cherepanova NA,Shrimal S,Gilmore R
MA3-019 was used in western blot to determine how N-glycosylation of cysteine-proximal acceptor sites in glycoproteins requires oxidoreductase activity
Mon Aug 18 00:00:00 EDT 2014
Transport of estradiol-17β-glucuronide, estrone-3-sulfate and taurocholate across the endoplasmic reticulum membrane: evidence for different transport systems.
Biochemical pharmacology
Wlcek K,Hofstetter L,Stieger B
MA3-019 was used in western blot to study the involvement of different systems in the ER transport of estradiol-17beta-glucuronide, estrone-3-sulfate and taurocholate
Sat Mar 01 00:00:00 EST 2014
Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligase implicated in Alzheimer's disease.
PloS one
Saito R,Kaneko M,Kitamura Y,Takata K,Kawada K,Okuma Y,Nomura Y
MA3-019 was used in western blot to study the effects of oxidative stress on the solubility of the Alzheimer's disease-associated E3 ubiquitin ligase HRD1
Thu Dec 18 00:00:00 EST 2014
mRNA redistribution during permanent focal cerebral ischemia.
Translational stroke research
Lewis MK,Jamison JT,Dunbar JC,DeGracia DJ
MA3-019 was used in immunohistochemistry to study mRNA granule formation following experimental permanent focal cerebral ischemia
Sun Dec 01 00:00:00 EST 2013
Depletion of molecular chaperones from the endoplasmic reticulum and fragmentation of the Golgi apparatus associated with pathogenesis in Pelizaeus-Merzbacher disease.
The Journal of biological chemistry
Numata Y,Morimura T,Nakamura S,Hirano E,Kure S,Goto YI,Inoue K
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Fri Mar 15 00:00:00 EDT 2013
Depletion of molecular chaperones from the endoplasmic reticulum and fragmentation of the Golgi apparatus associated with pathogenesis in Pelizaeus-Merzbacher disease.
The Journal of biological chemistry
Numata Y,Morimura T,Nakamura S,Hirano E,Kure S,Goto YI,Inoue K
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Fri Mar 15 00:00:00 EDT 2013
Depletion of molecular chaperones from the endoplasmic reticulum and fragmentation of the Golgi apparatus associated with pathogenesis in Pelizaeus-Merzbacher disease.
The Journal of biological chemistry
Numata Y,Morimura T,Nakamura S,Hirano E,Kure S,Goto YI,Inoue K
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Fri Mar 15 00:00:00 EDT 2013
Depletion of molecular chaperones from the endoplasmic reticulum and fragmentation of the Golgi apparatus associated with pathogenesis in Pelizaeus-Merzbacher disease.
The Journal of biological chemistry
Numata Y,Morimura T,Nakamura S,Hirano E,Kure S,Goto YI,Inoue K
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunocytochemistry
Fri Mar 15 00:00:00 EDT 2013
Unraveling the human dendritic cell phagosome proteome by organellar enrichment ranking.
Journal of proteomics
Buschow SI,Lasonder E,Szklarczyk R,Oud MM,de Vries IJ,Figdor CG
MA3-019 was used in western blot to study the protein composition of phagosomes from human dendritic cell phagosome
Thu Feb 16 00:00:00 EST 2012
Inhibiting rotavirus infection by membrane-impermeant thiol/disulfide exchange blockers and antibodies against protein disulfide isomerase.
Intervirology
Calderon MN,Guerrero CA,Acosta O,Lopez S,Arias CF
MA3-019 was used in flow cytometry to study the ability of non-cell-penetrating thiol-disulphide exchange inhibitors to reduce rotavirus infectivity and the potential involvement of protein disulfide isomerase
Mon Apr 08 00:00:00 EDT 2013
Organelles do not colocalize with mRNA granules in post-ischemic neurons.
Neuroscience
Jamison JT,Szymanski JJ,Degracia DJ
Published figure using PDI monoclonal antibody (Product # MA3-019) in Western Blot
Thu Dec 29 00:00:00 EST 2011
NLRP7, a nucleotide oligomerization domain-like receptor protein, is required for normal cytokine secretion and co-localizes with Golgi and the microtubule-organizing center.
The Journal of biological chemistry
Messaed C,Akoury E,Djuric U,Zeng J,Saleh M,Gilbert L,Seoud M,Qureshi S,Slim R
MA3-019 was used in immunocytochemistry to investigate the role of NLRP7 in normal cytokine secretion and its colocalization with Golgi
Fri Dec 16 00:00:00 EST 2011
NLRP7, a nucleotide oligomerization domain-like receptor protein, is required for normal cytokine secretion and co-localizes with Golgi and the microtubule-organizing center.
The Journal of biological chemistry
Messaed C,Akoury E,Djuric U,Zeng J,Saleh M,Gilbert L,Seoud M,Qureshi S,Slim R
MA3-019 was used in immunocytochemistry to investigate the role of NLRP7 in normal cytokine secretion and its colocalization with Golgi
Fri Dec 16 00:00:00 EST 2011
Elimination of hepatitis C virus from hepatocytes by a selective activation of therapeutic molecules.
PloS one
Wen X,Abe T,Kukihara H,Taguwa S,Mori Y,Tani H,Kato N,Suzuki T,Tatsumi M,Moriishi K,Matsuura Y
MA3-019 was used in immunocytochemistry to evaluate the efficacy of gene transfer therapy in clearing hepatitis C virus from hepatocytes
Thu Jan 06 00:00:00 EST 2011
Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kaneko M,Koike H,Saito R,Kitamura Y,Okuma Y,Nomura Y
MA3-019 was used in western blot to study role of protein degradation on endoplasmic reticulum stress and Alzheimer plaque deposits
Wed Mar 17 00:00:00 EDT 2010
mRNA escape from stress granule sequestration is dictated by localization to the endoplasmic reticulum.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Unsworth H,Raguz S,Edwards HJ,Higgins CF,Yagüe E
MA3-019 was used in western blot to investigate the process of mRNA translation during stress response
Wed Sep 01 00:00:00 EDT 2010
Characterization of the expression, localization, and secretion of PANDER in alpha-cells.
Molecular and cellular endocrinology
Carnegie JR,Robert-Cooperman CE,Wu J,Young RA,Wolf BA,Burkhardt BR
MA3-019 was used in immunocytochemistry to investigate the properties of PANDER in alpha-cells
Mon Aug 30 00:00:00 EDT 2010
Characterization of the expression, localization, and secretion of PANDER in alpha-cells.
Molecular and cellular endocrinology
Carnegie JR,Robert-Cooperman CE,Wu J,Young RA,Wolf BA,Burkhardt BR
MA3-019 was used in immunocytochemistry to investigate the properties of PANDER in alpha-cells
Mon Aug 30 00:00:00 EDT 2010
DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation.
Molecular immunology
Eleveld-Trancikova D,Sanecka A,van Hout-Kuijer MA,Looman MW,Hendriks IA,Jansen BJ,Adema GJ
MA3-019 was used in immunocytochemistry to study the interaction between DC-STAMP interacts and estrogen receptor-resident transcription factor LUMAN
Thu Jul 01 00:00:00 EDT 2010
Mobile ER-to-Golgi but not post-Golgi membrane transport carriers disappear during the terminal myogenic differentiation.
Cell and tissue research
Nevalainen M,Kaisto T,Metsikkö K
MA3-019 was used in immunocytochemistry to investigate the difference of ER-to-Golgi trafficking between adult skeletal myofibers and other mammalian cell types
Fri Oct 01 00:00:00 EDT 2010
Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
Pyle AL,Li B,Maupin AB,Guzman RJ,Crimmins DL,Olson S,Atkinson JB,Young PP
MA3-019 was used in immunocytochemistry to study the role of biomechanical stress in vascular pathologies
Tue May 04 00:00:00 EDT 2010
Membrane topology of human AGPAT3 (LPAAT3).
Biochemical and biophysical research communications
Schmidt JA,Yvone GM,Brown WJ
MA3-019 was used in immunocytochemistry to investigate the structural arrangement of AGPAT3 in membrane and its significance in the enzymatic activity
Fri Jul 09 00:00:00 EDT 2010
Regulation of ER molecular chaperone prevents bone loss in a murine model for osteoporosis.
Journal of bone and mineral metabolism
Hino S,Kondo S,Yoshinaga K,Saito A,Murakami T,Kanemoto S,Sekiya H,Chihara K,Aikawa Y,Hara H,Kudo T,Sekimoto T,Funamoto T,Chosa E,Imaizumi K
MA3-019 was used in immunohistochemistry to investigate the effect of endoplasmic reticulum stress on bone balance in a mouse osteoporosis model
Mon Mar 01 00:00:00 EST 2010
Production of anti-carbohydrate antibodies by phage display technologies: potential impairment of cell growth as a result of endogenous expression.
The Journal of biological chemistry
Yuasa N,Zhang W,Goto T,Sakaue H,Matsumoto-Takasaki A,Kimura M,Ohshima H,Tsuchida Y,Koizumi T,Sakai K,Kojima T,Yamamoto K,Nakata M,Fujita-Yamaguchi Y
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Fri Oct 01 00:00:00 EDT 2010
Production of anti-carbohydrate antibodies by phage display technologies: potential impairment of cell growth as a result of endogenous expression.
The Journal of biological chemistry
Yuasa N,Zhang W,Goto T,Sakaue H,Matsumoto-Takasaki A,Kimura M,Ohshima H,Tsuchida Y,Koizumi T,Sakai K,Kojima T,Yamamoto K,Nakata M,Fujita-Yamaguchi Y
Published figure using PDI monoclonal antibody (Product # MA3-019) in Immunofluorescence
Fri Oct 01 00:00:00 EDT 2010
Calsyntenins mediate TGN exit of APP in a kinesin-1-dependent manner.
Traffic (Copenhagen, Denmark)
Ludwig A,Blume J,Diep TM,Yuan J,Mateos JM,Leuthäuser K,Steuble M,Streit P,Sonderegger P
MA3-019 was used in immunocytochemistry to study the role kinesisn-1 in the calsyntenin-mediated trans-Golgi network exit of amyloid precursor protein
Fri May 01 00:00:00 EDT 2009
Protein disulfide isomerase (PDI) associates with NADPH oxidase and is required for phagocytosis of Leishmania chagasi promastigotes by macrophages.
Journal of leukocyte biology
Santos CX,Stolf BS,Takemoto PV,Amanso AM,Lopes LR,Souza EB,Goto H,Laurindo FR
MA3-019 was used in immunoprecipitation to investigate the role of protein disulfide isomerase (PDI) during phagocytosis of Leishmania chagasi promastigotes by macrophages
Thu Oct 01 00:00:00 EDT 2009
Protein disulfide isomerase (PDI) associates with NADPH oxidase and is required for phagocytosis of Leishmania chagasi promastigotes by macrophages.
Journal of leukocyte biology
Santos CX,Stolf BS,Takemoto PV,Amanso AM,Lopes LR,Souza EB,Goto H,Laurindo FR
MA3-019 was used in immunoprecipitation to investigate the role of protein disulfide isomerase (PDI) during phagocytosis of Leishmania chagasi promastigotes by macrophages
Thu Oct 01 00:00:00 EDT 2009
Protein disulfide isomerase (PDI) associates with NADPH oxidase and is required for phagocytosis of Leishmania chagasi promastigotes by macrophages.
Journal of leukocyte biology
Santos CX,Stolf BS,Takemoto PV,Amanso AM,Lopes LR,Souza EB,Goto H,Laurindo FR
MA3-019 was used in immunoprecipitation to investigate the role of protein disulfide isomerase (PDI) during phagocytosis of Leishmania chagasi promastigotes by macrophages
Thu Oct 01 00:00:00 EDT 2009
Dynamics of somatostatin type 2A receptor cargoes in living hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Lelouvier B,Tamagno G,Kaindl AM,Roland A,Lelievre V,Le Verche V,Loudes C,Gressens P,Faivre-Baumann A,Lenkei Z,Dournaud P
MA3-019 was used in immunocytochemistry to investigate the intracellular trafficking of somatostatin type 2A receptor cargoes in living hippocampal neurons.
Wed Apr 23 00:00:00 EDT 2008
Interaction and functional association of protein disulfide isomerase with alphaVbeta3 integrin on endothelial cells.
The FEBS journal
Swiatkowska M,Szymański J,Padula G,Cierniewski CS
Published figure using PDI monoclonal antibody (Product # MA3-019) in Neutralization
Tue Apr 01 00:00:00 EDT 2008
Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK.
The Journal of biological chemistry
Yamaguchi Y,Larkin D,Lara-Lemus R,Ramos-Castañeda J,Liu M,Arvan P
MA3-019 was used in western blot to study the relationship between endoplasmic reticulum chaperone regulation and the endoplasmic reticulum stress response kinase PERK.
Fri Jun 20 00:00:00 EDT 2008
Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK.
The Journal of biological chemistry
Yamaguchi Y,Larkin D,Lara-Lemus R,Ramos-Castañeda J,Liu M,Arvan P
MA3-019 was used in western blot to study the relationship between endoplasmic reticulum chaperone regulation and the endoplasmic reticulum stress response kinase PERK.
Fri Jun 20 00:00:00 EDT 2008
Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.
Molecular & cellular proteomics : MCP
Gramolini AO,Kislinger T,Alikhani-Koopaei R,Fong V,Thompson NJ,Isserlin R,Sharma P,Oudit GY,Trivieri MG,Fagan A,Kannan A,Higgins DG,Huedig H,Hess G,Arab S,Seidman JG,Seidman CE,Frey B,Perry M,Backx PH,Liu PP,MacLennan DH,Emili A
MA3-019 was used in western blot to perform the global proteomics surveys of cardiac ventricle of a phospholamban mutant mouse
Sat Mar 01 00:00:00 EST 2008
Activated somatostatin type 2 receptors traffic in vivo in central neurons from dendrites to the trans Golgi before recycling.
Traffic (Copenhagen, Denmark)
Csaba Z,Lelouvier B,Viollet C,El Ghouzzi V,Toyama K,Videau C,Bernard V,Dournaud P
MA3-019 was used in immunohistochemistry to investigate the trafficking and recycling of activated somatostatin type 2 receptors in vivo in central neurons
Sun Jul 01 00:00:00 EDT 2007
The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum.
Journal of leukocyte biology
Eleveld-Trancikova D,Triantis V,Moulin V,Looman MW,Wijers M,Fransen JA,Lemckert AA,Havenga MJ,Figdor CG,Janssen RA,Adema GJ
MA3-019 was used in immunocytochemistry to characterize the dendritic cell-derived protein DC-STAMP
Tue Mar 01 00:00:00 EST 2005
The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum.
Journal of leukocyte biology
Eleveld-Trancikova D,Triantis V,Moulin V,Looman MW,Wijers M,Fransen JA,Lemckert AA,Havenga MJ,Figdor CG,Janssen RA,Adema GJ
MA3-019 was used in immunocytochemistry to characterize the dendritic cell-derived protein DC-STAMP
Tue Mar 01 00:00:00 EST 2005
Restricted distribution of mRNAs encoding a sarcoplasmic reticulum or transverse tubule protein in skeletal myofibers.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Nissinen M,Kaisto T,Salmela P,Peltonen J,Metsikkö K
MA3-019 was used in immunohistochemistry to investigate the distribution of CSQ and DHPR proteins and corresponding mRNAs during myogenic development
Tue Feb 01 00:00:00 EST 2005
A cellular UDP-glucose deficiency causes overexpression of glucose/oxygen-regulated proteins independent of the endoplasmic reticulum stress elements.
The Journal of biological chemistry
Flores-Diaz M,Higuita JC,Florin I,Okada T,Pollesello P,Bergman T,Thelestam M,Mori K,Alape-Giron A
MA3-019 was used in western blot to determine the effect of cellular UDP-Glc level on stress protein expression.
Fri May 21 00:00:00 EDT 2004
Intracellularly located misfolded glycoprotein hormone receptors associate with different chaperone proteins than their cognate wild-type receptors.
Molecular endocrinology (Baltimore, Md.)
Mizrachi D,Segaloff DL
MA3-019 was used in immunoprecipitation to study the folding of the glycoprotein hormone receptors and their misfolded mutants .
Thu Jul 01 00:00:00 EDT 2004
Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1.
Blood
Lahav J,Wijnen EM,Hess O,Hamaia SW,Griffiths D,Makris M,Knight CG,Essex DW,Farndale RW
MA3-019 was used in blocking/activating experiment to investigate the role of enzymatically catalyzed disulfide exchange for platelet adhesion to collagen via integrin alpha2beta1
Mon Sep 15 00:00:00 EDT 2003
Protein disulfide isomerase, a component of the estrogen receptor complex, is associated with Chlamydia trachomatis serovar E attached to human endometrial epithelial cells.
Infection and immunity
Davis CH,Raulston JE,Wyrick PB
MA3-019 was used in blocking/activating experiment to investigate the role of protein disulfide isomerase in the infectivity of Chlamydia trachomatis serovar E
Mon Jul 01 00:00:00 EDT 2002
Structural requirements for the apical sorting of human multidrug resistance protein 2 (ABCC2).
European journal of biochemistry
Nies AT,König J,Cui Y,Brom M,Spring H,Keppler D
MA3-019 was used in immunocytochemistry to perform structural analysis to identify the necessary components for apical sorting of human MRP2
Mon Apr 01 00:00:00 EST 2002
Selective intracellular retention of extracellular matrix proteins and chaperones associated with pseudoachondroplasia.
Matrix biology : journal of the International Society for Matrix Biology
Vranka J,Mokashi A,Keene DR,Tufa S,Corson G,Sussman M,Horton WA,Maddox K,Sakai L,Bächinger HP
MA3-019 was used in immunohistochemistry to study the mechanism for the cytoplasmic accumulation of extracellular matrix proteins and chaperones associated in pseudoachondroplasia
Thu Nov 01 00:00:00 EST 2001
Dimerization of P-selectin in platelets and endothelial cells.
Blood
Barkalow FJ,Barkalow KL,Mayadas TN
MA3-019 was used in western blot to investigate P-selectin dimerization in human umbilical vein endothelial cells and resting platelets and the unique properties of the dimers.
Wed Nov 01 00:00:00 EST 2000
Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes.
Journal of immunology (Baltimore, Md. : 1950)
Bennett TA,Edwards BS,Sklar LA,Rogelj S
MA3-019 was used in immunocytochemistry to study the expression and the function of protein-disulfide isomerase.
Sat Apr 15 00:00:00 EDT 2000
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.jpg?time=20220826?time=20220826 "PDI Antibody (MA3-019) in WB")
