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Invitrogen
Phospho-CrkL (Tyr207) Recombinant Rabbit Monoclonal Antibody (4H24L33)
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
Phospho-CrkL (Tyr207) Antibody (702815) in ICC/IF
For immunofluorescence analysis, K562 cells were fixed and unpermeabilized for detection of endogenous CrKL pY207 using Anti-CrKL pY207 Recombinant Rabbit Monoclonal Antibody (Product # 702815, 1:100 dilution) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Nuclei (blue) is stained using SlowFade® Gold Antifade Mount... View More
Product Details
702815
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
4H24L33
Immunogen
Peptide corresponding to human phospho-CRKL (Tyr207) [aa204-aa210]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2734824
Product Specific Information
This antibody is predicted to react with Monkey, Cat, Horse, Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
May mediate the transduction of intracellular signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Crk-like protein; OTTHUMP00000198539; v-crk avian sarcoma virus CT10 oncogene homolog-like
Gene Aliases: CRKL
UniProt ID: (Human) P46109
Entrez Gene ID: (Human) 1399
activation of MAPKK activity
blood vessel development
JNK cascade
Ras protein signal transduction
heart development
positive regulation of cell proliferation
organ morphogenesis
anterior/posterior pattern specification
intracellular signal transduction
thymus development
parathyroid gland development
cell-cell adhesion
positive regulation of substrate adhesion-dependent cell spreading
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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