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Phospho-GKAP1 (Ser25) Antibody (PA5-105217) in IHC (P)
Immunohistochemistry analysis of Phospho-GKAP1 (Ser25) in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-GKAP1 (Ser25) polyclonal antibody (Product # PA5-105217) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-105217
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GKAP1(Accession Q5VSY0), corresponding to amino acid residues around phosphorylated Ser25.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2816690
Product Specific Information
Antibody detects endogenous levels of GKAP only when phosphorylated at Ser25.
Target Information
The approximately 142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 42 kD cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase anchoring protein 42kDa; cGMP-dependent protein kinase-anchoring protein of 42 kDa; G kinase-anchoring protein 1; protein kinase anchoring protein GKAP42
Gene Aliases: 42kDa; 4933400B15Rik; D13Ertd340e; FKSG21; GKAP1; GKAP42
UniProt ID: (Human) Q5VSY0, (Mouse) Q9JMB0, (Rat) Q5XIG5
Entrez Gene ID: (Human) 80318, (Mouse) 56278, (Rat) 361202
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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