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Product Details
PA5-40228
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human Intestinal Cell Kinase around the phosphorylation site of Y159.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2577141
Product Specific Information
This antibody is predicted to react with human and rat based on sequence homology.
Target Information
ICK or intestinal cell kinase belongs to a very extensive family of proteins that share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. ICK localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. ICK purified from transfected human embryonic kidney cells undergoes autophosphorylation and phosphorylates a test protein. ICK plays a key role in development of central nervous, skeletal, and endocrine systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ciliogenesis associated kinase 1; heart serine-threonine protein kinase; hICK; Intestinal cell kinase; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; mICK; MRK; serine/threonine protein kinase; Serine/threonine-protein kinase ICK
Gene Aliases: 2210420N10Rik; AI848300; CILK1; ECO; ICK; KIAA0936; LCK2; MRK
UniProt ID: (Human) Q9UPZ9, (Rat) Q62726, (Mouse) Q9JKV2
Entrez Gene ID: (Human) 22858, (Rat) 84411, (Mouse) 56542
magnesium ion binding
protein serine/threonine kinase activity
cyclin-dependent protein serine/threonine kinase activity
protein binding
ATP binding
metal ion binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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