Invitrogen

Phospho-JunB (Thr255) Polyclonal Antibody

View all (33) JunB antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-105510

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human JUNB(Accession P17275), corresponding to amino acid residues around phosphorylated Thr255.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816938

Product Specific Information

Antibody detects endogenous levels of JunB only when phosphorylated at Thr255.

Target Information

JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: activator protein 1; Jun B; jun B proto-oncogene; Jun-B oncogene; MyD21; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; transcription factor jun-B; Transcription factor JunB

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Gene Aliases: AP-1; Jun-b; JUNB

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UniProt ID: (Human) P17275, (Rat) P24898, (Mouse) P09450

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Entrez Gene ID: (Human) 3726, (Rat) 24517, (Mouse) 16477

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription coactivator activity transcription corepressor activity protein binding transcription factor binding RNA polymerase II regulatory region sequence-specific DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding protein heterodimerization activity basic leucine zipper transcription factor
Process(es)
negative regulation of transcription from RNA polymerase II promoter vasculogenesis osteoblast differentiation trophectodermal cell differentiation regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter response to radiation response to light stimulus response to mechanical stimulus regulation of cell death osteoclast differentiation response to lipopolysaccharide response to progesterone cellular response to hormone stimulus osteoblast proliferation response to cytokine regulation of cell proliferation response to drug response to peptide hormone positive regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter decidualization response to corticosterone response to cAMP regulation of cell cycle embryonic process involved in female pregnancy labyrinthine layer blood vessel development cellular response to calcium ion in utero embryonic development regulation of transcription, DNA-templated female pregnancy cellular process response to organic cyclic compound transcription, DNA-templated
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