Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-64715
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SRC-1 (Phospho-Thr1179)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2663075
Product Specific Information
Phospho-SRC1 (Thr1179) Polyclonal Antibody detects endogenous levels of SRC1 only when phosphorylated at Thr1179.
Target Information
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ASV; bHLHe74; c-SRC; Class E basic helix-loop-helix protein 74; Hin-2 protein; mNRC-1; NCoA-1; Nuclear receptor coactivator 1; Nuclear receptor coactivator protein 1; PAX3/NCOA1 fusion protein; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; SRC-1; SRC-1 (-Q); SRC-a/NCoA-1; Steroid receptor coactivator 1; steroid receptor coactivator-1
Gene Aliases: bHLHe42; BHLHE74; F-SRC-1; KAT13A; NCOA1; RIP160; SRC-1; SRC1
UniProt ID: (Human) Q15788, (Mouse) P70365
Entrez Gene ID: (Human) 8648, (Mouse) 17977
RNA polymerase II regulatory region DNA binding
RNA polymerase II transcription coactivator activity
chromatin binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
ligand-dependent nuclear receptor binding
enzyme binding
estrogen receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
protein complex binding
progesterone receptor binding
nuclear hormone receptor binding
retinoid X receptor binding
protein dimerization activity
protein N-terminus binding
androgen receptor binding
DNA binding
signal transducer activity
transcription factor binding
transferase activity
transferase activity, transferring acyl groups
retinoic acid receptor binding
histone modifying enzyme
positive regulation of transcription from RNA polymerase II promoter by galactose
regulation of thyroid hormone mediated signaling pathway
transcription, DNA-templated
lactation
male gonad development
bile acid and bile salt transport
cerebellum development
hippocampus development
hypothalamus development
cerebral cortex development
androgen receptor signaling pathway
intracellular receptor signaling pathway
response to estradiol
response to retinoic acid
response to progesterone
cellular response to hormone stimulus
positive regulation of apoptotic process
histone H4 acetylation
cellular lipid metabolic process
estrous cycle
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
male mating behavior
labyrinthine layer morphogenesis
cellular response to Thyroglobulin triiodothyronine
regulation of cellular response to drug
regulation of transcription, DNA-templated
signal transduction
regulation of nucleic acid-templated transcription
regulation of RNA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support