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Phospho-TYK2 (Tyr1054, Tyr1055) Antibody (PA5-85309) in ICC/IF
Immunocytochemistry analysis of Phospho-TYK2 (Tyr1054, Tyr1055) in 4% paraformaldehyde-fixed HeLa cells using Phospho-TYK2 (Tyr1054, Tyr1055) polyclonal antibody (Product # PA5-85309) at a dilution of 1:2000. Sample was then incubated with alpha tubulin secondary antibody (red).
Product Details
PA5-85309
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human TYK2.
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792451
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Pig (84%), Bovine (85%).
Positive Control: Target recombinant protein.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2
Gene Aliases: IMD35; JTK1; TYK2
UniProt ID: (Human) P29597
Entrez Gene ID: (Human) 7297
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
cell migration
cell differentiation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
type I interferon signaling pathway
regulation of type I interferon-mediated signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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