Product References
Herpes Simplex Virus Type 1 Induces AD-like Neurodegeneration Markers in Human Progenitor and Differentiated ReNcell VM Cells.
Microorganisms
Salgado B,Sastre I,Bullido MJ,Aldudo J
44-738G was used in Western Blotting and Immunocytochemistry to support the use of this cell line to generate a new research platform for investigating AD neuropathology and its most significant risk factors, which may lead to important discoveries in the context of this highly impactful disease.
Thu May 04 00:00:00 EDT 2023
Herpes Simplex Virus Type 1 Induces AD-like Neurodegeneration Markers in Human Progenitor and Differentiated ReNcell VM Cells.
Microorganisms
Salgado B,Sastre I,Bullido MJ,Aldudo J
44-738G was used in Western Blotting and Immunocytochemistry to support the use of this cell line to generate a new research platform for investigating AD neuropathology and its most significant risk factors, which may lead to important discoveries in the context of this highly impactful disease.
Thu May 04 00:00:00 EDT 2023
Herpes Simplex Virus Type 1 Induces AD-like Neurodegeneration Markers in Human Progenitor and Differentiated ReNcell VM Cells.
Microorganisms
Salgado B,Sastre I,Bullido MJ,Aldudo J
44-738G was used in Western Blotting and Immunocytochemistry to support the use of this cell line to generate a new research platform for investigating AD neuropathology and its most significant risk factors, which may lead to important discoveries in the context of this highly impactful disease.
Thu May 04 00:00:00 EDT 2023
Direct and Indirect Effects of Filamin A on Tau Pathology in Neuronal Cells.
Molecular neurobiology
Levert S,Pilliod J,Aumont É,Armanville S,Tremblay C,Calon F,Leclerc N
44-738G was used in Western Blotting to indicate that in Tauopathies, FLNA could contribute to Tau pathology by acting on Tau and annexin A2.
Wed Feb 01 00:00:00 EST 2023
Branched-Chain Amino Acids Are Linked with Alzheimer's Disease-Related Pathology and Cognitive Deficits.
Cells
Siddik MAB,Mullins CA,Kramer A,Shah H,Gannaban RB,Zabet-Moghaddam M,Huebinger RM,Hegde VK,MohanKumar SMJ,MohanKumar PS,Shin AC
Published figure using Phospho-Tau (Thr205) polyclonal antibody (Product # 44-738G) in Western Blot
Mon Nov 07 00:00:00 EST 2022
Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates.
The EMBO journal
Hochmair J,Exner C,Franck M,Dominguez-Baquero A,Diez L,Brognaro H,Kraushar ML,Mielke T,Radbruch H,Kaniyappan S,Falke S,Mandelkow E,Betzel C,Wegmann S
Published figure using Phospho-Tau (Thr205) polyclonal antibody (Product # 44-738G) in Western Blot
Wed Jun 01 00:00:00 EDT 2022
Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females.
Cells
Pan AL,Audrain M,Sakakibara E,Joshi R,Zhu X,Wang Q,Wang M,Beckmann ND,Schadt EE,Gandy S,Zhang B,Ehrlich ME,Salton SR
44-738G was used in Immunocytochemistry, Immunohistochemistry, Western Blot to suggest that that gender-specific interventions may be indicated in the treatment of Alzheimer’s disease.
Thu Dec 01 00:00:00 EST 2022
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components.
Neuron
Lester E,Ooi FK,Bakkar N,Ayers J,Woerman AL,Wheeler J,Bowser R,Carlson GA,Prusiner SB,Parker R
44-738G was used in Immunoprecipitation to identify tau alteration of nuclear speckles as a feature of tau aggregation that may contribute to the pathology of tau aggregates.
Wed May 19 00:00:00 EDT 2021
RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation.
Cell death and differentiation
Zhao D,Zhou Y,Huo Y,Meng J,Xiao X,Han L,Zhang X,Luo H,Can D,Sun H,Huang TY,Wang X,Zhang J,Liu FR,Xu H,Zhang YW
44-738G was used in Western Blot to observe retarded axon outgrowth, elevated p35 and p25 protein levels, and increased tau phosphorylation at major Cdk5 phosphorylation sites in Rps23rg1 knockout (KO) mice.
Fri Jan 01 00:00:00 EST 2021
β-amyloid and tau pathology in the aging feline brain.
The Journal of comparative neurology
Fiock KL,Smith JD,Crary JF,Hefti MM
44-738G was used in Immunohistochemistry (Paraffin) to propose that the development of β-amyloid and tau pathology in ageing domestic cats is similar to human Alzheimer's disease and could serve as a model.
Wed Jan 01 00:00:00 EST 2020
Oxidative stress differentially induces tau dissociation from neuronal microtubules in neurites of neurons cultured from different regions of the embryonic Gallus domesticus brain.
Journal of neuroscience research
Beyrent E,Gomez G
44-738G was used in Immunocytochemistry-immunofluorescence to suggest that oxidative stress induces changes in tau protein that precede cytoskeletal degradation and neurite retraction.
Wed Apr 01 00:00:00 EDT 2020
Oxidative stress differentially induces tau dissociation from neuronal microtubules in neurites of neurons cultured from different regions of the embryonic Gallus domesticus brain.
Journal of neuroscience research
Beyrent E,Gomez G
44-738G was used in Immunocytochemistry-immunofluorescence to suggest that oxidative stress induces changes in tau protein that precede cytoskeletal degradation and neurite retraction.
Wed Apr 01 00:00:00 EDT 2020
Truncation of Tau selectively facilitates its pathological activities.
The Journal of biological chemistry
Gu J,Xu W,Jin N,Li L,Zhou Y,Chu D,Gong CX,Iqbal K,Liu F
44-738G was used in Western Blotting to suggest that the first 150 aa and the last 50 aa protect Tau from pathological characteristics and that their deletions facilitate pathological activities.
Fri Oct 02 00:00:00 EDT 2020
Pathological Tau From Alzheimer's Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo.
Frontiers in aging neuroscience
Miao J,Shi R,Li L,Chen F,Zhou Y,Tung YC,Hu W,Gong CX,Iqbal K,Liu F
44-738G was used in Western Blotting to speculate that AD P-tau seeds hyperphosphorylated tau to form aggregates, which resist to the dephosphorylation by PP2A, resulting in hyperphosphorylation and pathology of tau.
Thu Oct 01 00:00:00 EDT 2020
GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease.
Journal of clinical medicine
Ko HJ,Chiou SJ,Wong YH,Wang YH,Lai Y,Chou CH,Wang C,Loh JK,Lieu AS,Cheng JT,Lin YT,Lu PJ,Fann MJ,Huang CF,Hong YR
Published figure using Phospho-Tau (Thr205) polyclonal antibody (Product # 44-738G) in Western Blot
Mon Oct 21 00:00:00 EDT 2019
Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice.
Scientific reports
Zhang Y,Wu F,Iqbal K,Gong CX,Hu W,Liu F
44-738G was used in Western Blotting to characterise Alzheimer-like alterations behaviourally, biochemically and immunohistochemically 6 weeks and 7 months after unilateral mild-to-moderate controlled cortical impact in human tau transgenic mice.
Thu Mar 07 00:00:00 EST 2019
Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer's Disease.
Frontiers in aging neuroscience
Zhou Y,Shi J,Chu D,Hu W,Guan Z,Gong CX,Iqbal K,Liu F
Published figure using Phospho-Tau (Thr205) polyclonal antibody (Product # 44-738G) in Western Blot
Sat Apr 09 00:00:00 EDT 2022
Quercetin inhibits okadaic acid-induced tau protein hyperphosphorylation through the Ca2+‑calpain‑p25‑CDK5 pathway in HT22 cells.
International journal of molecular medicine
Shen XY,Luo T,Li S,Ting OY,He F,Xu J,Wang HQ
44-738G was used in Western Blotting to expore the inhibitory effect of QUE on okadaic acid-induced tau protein hyperphosphorylation in HT22 cells.
Thu Feb 01 00:00:00 EST 2018
Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury.
Journal of Alzheimer's disease : JAD
Hu W,Tung YC,Zhang Y,Liu F,Iqbal K
44-738G was used in Western Blotting to test the effect of repetitive mild traumatic brain injury on tau hyperphosphorylation, in triple-transgenic mouse model of Alzheimer's disease.
Mon Jul 15 00:00:00 EDT 2019
Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury.
Journal of Alzheimer's disease : JAD
Hu W,Tung YC,Zhang Y,Liu F,Iqbal K
44-738G was used in Western Blotting to test the effect of repetitive mild traumatic brain injury on tau hyperphosphorylation, in triple-transgenic mouse model of Alzheimer's disease.
Mon Jul 15 00:00:00 EDT 2019
Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis.
Frontiers in aging neuroscience
Hu W,Wu F,Zhang Y,Gong CX,Iqbal K,Liu F
44-738G was used in Dot blot to provide the regional expression profiles of tau and tau pathology-related proteins in the brain.
Thu Oct 01 00:00:00 EDT 2020
Tau secretion is correlated to an increase of Golgi dynamics.
PloS one
Mohamed NV,Desjardins A,Leclerc N
Published figure using Phospho-Tau (Thr205) polyclonal antibody (Product # 44-738G) in Western Blot
Mon Sep 18 00:00:00 EDT 2017
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma.
BMC neuroscience
O'Hare Doig RL,Chiha W,Giacci MK,Yates NJ,Bartlett CA,Smith NM,Hodgetts SI,Harvey AR,Fitzgerald M
44-738G was used in Immunohistochemistry on frozen tissues to determine how flux through specific ion channels contributes to the various pathologies, using partial optic nerve transection in adult female rats to model secondary degeneration following neurotrauma.
Mon Aug 14 00:00:00 EDT 2017
Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration.
Proceedings of the National Academy of Sciences of the United States of America
Wang AC,Jensen EH,Rexach JE,Vinters HV,Hsieh-Wilson LC
44-738G was used in immunohistochemistry to characterize mice with a forebrain-specific loss of O-GlcNAc glycosylation
Tue Dec 27 00:00:00 EST 2016
Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma.
The American journal of pathology
Winston CN,Noël A,Neustadtl A,Parsadanian M,Barton DJ,Chellappa D,Wilkins TE,Alikhani AD,Zapple DN,Villapol S,Planel E,Burns MP
44-738G was used in western blot to characterize chronic white matter inflammation and dendritic spine loss in a mouse model of highly repetitive head trauma
Tue Mar 01 00:00:00 EST 2016
Human Truncated Tau Induces Mature Neurofibrillary Pathology in a Mouse Model of Human Tauopathy.
Journal of Alzheimer's disease : JAD
Zimova I,Brezovakova V,Hromadka T,Weisova P,Cubinkova V,Valachova B,Filipcik P,Jadhav S,Smolek T,Novak M,Zilka N
44738G was used in western blot to describe the molecular and behavioral features of R3m/4 transgenic mice expressing human non-mutated truncated tau protein and assess these mice as a model for Alzheimer's disease
Tue Sep 06 00:00:00 EDT 2016
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
The Journal of comparative neurology
Smolek T,Madari A,Farbakova J,Kandrac O,Jadhav S,Cente M,Brezovakova V,Novak M,Zilka N
44-738G was used in immunohistochemistry - paraffin section and western blot to study canine cognitive impairment syndrome.
Tue Mar 01 00:00:00 EST 2016
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
The Journal of comparative neurology
Smolek T,Madari A,Farbakova J,Kandrac O,Jadhav S,Cente M,Brezovakova V,Novak M,Zilka N
44-738G was used in immunohistochemistry - paraffin section and western blot to study canine cognitive impairment syndrome.
Tue Mar 01 00:00:00 EST 2016
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
The Journal of comparative neurology
Smolek T,Madari A,Farbakova J,Kandrac O,Jadhav S,Cente M,Brezovakova V,Novak M,Zilka N
44-738G was used in immunohistochemistry - paraffin section and western blot to study canine cognitive impairment syndrome.
Tue Mar 01 00:00:00 EST 2016
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
The Journal of comparative neurology
Smolek T,Madari A,Farbakova J,Kandrac O,Jadhav S,Cente M,Brezovakova V,Novak M,Zilka N
44-738G was used in immunohistochemistry - paraffin section and western blot to study canine cognitive impairment syndrome.
Tue Mar 01 00:00:00 EST 2016
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
The Journal of comparative neurology
Smolek T,Madari A,Farbakova J,Kandrac O,Jadhav S,Cente M,Brezovakova V,Novak M,Zilka N
44-738G was used in immunohistochemistry - paraffin section and western blot to study canine cognitive impairment syndrome.
Tue Mar 01 00:00:00 EST 2016
Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation.
Neurobiology of aging
Wang Y,Yang R,Gu J,Yin X,Jin N,Xie S,Wang Y,Chang H,Qian W,Shi J,Iqbal K,Gong CX,Cheng C,Liu F
44-738G was used in western blot to study the role of glycogen synthase kinase-3beta and protein phosphatase 2A in regulation of tau hyperphosphorylation
Thu Jan 01 00:00:00 EST 2015
Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis.
BMC cancer
Grant NJ,Coates PJ,Woods YL,Bray SE,Morrice NA,Hastie CJ,Lamont DJ,Carey FA,Sutherland C
44-738G was used in immunocytochemistry to discuss the use of CDK5 biomarkers
Tue Nov 10 00:00:00 EST 2015
Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis.
BMC cancer
Grant NJ,Coates PJ,Woods YL,Bray SE,Morrice NA,Hastie CJ,Lamont DJ,Carey FA,Sutherland C
44-738G was used in immunocytochemistry to discuss the use of CDK5 biomarkers
Tue Nov 10 00:00:00 EST 2015
Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation.
Scientific reports
Wang Y,Zhang Y,Hu W,Xie S,Gong CX,Iqbal K,Liu F
44-738G was used in western blot to characterize postmortem behavior and the rapid alteration of protein phosphorylation
Thu Oct 29 00:00:00 EDT 2015
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.
Nature communications
Takeda S,Wegmann S,Cho H,DeVos SL,Commins C,Roe AD,Nicholls SB,Carlson GA,Pitstick R,Nobuhara CK,Costantino I,Frosch MP,Müller DJ,Irimia D,Hyman BT
44-738G was used in western blot to research Alzheimer's disease brain and neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau
Tue Oct 13 00:00:00 EDT 2015
Amyloid and tau pathology of familial Alzheimer's disease APP/PS1 mouse model in a senescence phenotype background (SAMP8).
Age (Dordrecht, Netherlands)
Porquet D,Andrés-Benito P,Griñán-Ferré C,Camins A,Ferrer I,Canudas AM,Del Valle J,Pallàs M
44-738G was used in western blot to characterize cognitive and neuropathological Alzheimer's disease markers in a novel mouse model
Sun Feb 01 00:00:00 EST 2015
Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions.
PloS one
Petry FR,Pelletier J,Bretteville A,Morin F,Calon F,Hébert SS,Whittington RA,Planel E
Published figure using Phospho-Tau (Thr205) polyclonal antibody (Product # 44-738G) in Western Blot
Mon Dec 22 00:00:00 EST 2014
Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.
Biochimica et biophysica acta
Pedrós I,Petrov D,Allgaier M,Sureda F,Barroso E,Beas-Zarate C,Auladell C,Pallàs M,Vázquez-Carrera M,Casadesús G,Folch J,Camins A
44-738G was used in western blot to investigate the abnormalites in hippocampal energy metabolism in the pathogenesis of Alzheimer disease.
Mon Sep 01 00:00:00 EDT 2014
MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Absalon S,Kochanek DM,Raghavan V,Krichevsky AM
44-738G was used in western blot to investigate the role of MiR-26b in cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons.
Wed Sep 11 00:00:00 EDT 2013
An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.
Acta neuropathologica
Bolognin S,Blanchard J,Wang X,Basurto-Islas G,Tung YC,Kohlbrenner E,Grundke-Iqbal I,Iqbal K
44-738G was used in immunohistochemistry - free floating and western blot to report that expression of the N-terminal I2NTF and C-terminal I2CTF halves of I2PP2A in rat brain reproduced key features of Alzheimer's disease
Sun Jan 01 00:00:00 EST 2012
The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang X,Blanchard J,Kohlbrenner E,Clement N,Linden RM,Radu A,Grundke-Iqbal I,Iqbal K
Mon Nov 01 00:00:00 EDT 2010
The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang X,Blanchard J,Kohlbrenner E,Clement N,Linden RM,Radu A,Grundke-Iqbal I,Iqbal K
Mon Nov 01 00:00:00 EDT 2010
Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases.
Journal of neurochemistry
Yu Y,Run X,Liang Z,Li Y,Liu F,Liu Y,Iqbal K,Grundke-Iqbal I,Gong CX
Published figure using Phospho-Tau (Thr205) polyclonal antibody (Product # 44-738G) in Western Blot
Sun Mar 01 00:00:00 EST 2009
Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases.
Journal of neurochemistry
Yu Y,Run X,Liang Z,Li Y,Liu F,Liu Y,Iqbal K,Grundke-Iqbal I,Gong CX
Published figure using Phospho-Tau (Thr205) polyclonal antibody (Product # 44-738G) in Western Blot
Sun Mar 01 00:00:00 EST 2009
Increased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalities.
Molecular and cellular biology
Lambourne SL,Sellers LA,Bush TG,Choudhury SK,Emson PC,Suh YH,Wilkinson LS
Sat Jan 01 00:00:00 EST 2005
Dephosphorylation of tau by protein phosphatase 5: impairment in Alzheimer's disease.
The Journal of biological chemistry
Liu F,Iqbal K,Grundke-Iqbal I,Rossie S,Gong CX
Fri Jan 21 00:00:00 EST 2005
Pseudophosphorylation of tau protein alters its ability for self-aggregation.
Journal of neurochemistry
Haase C,Stieler JT,Arendt T,Holzer M
Mon Mar 01 00:00:00 EST 2004
Pseudophosphorylation of tau protein alters its ability for self-aggregation.
Journal of neurochemistry
Haase C,Stieler JT,Arendt T,Holzer M
Mon Mar 01 00:00:00 EST 2004
Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein.
The Journal of biological chemistry
Alonso AD,Zaidi T,Novak M,Barra HS,Grundke-Iqbal I,Iqbal K
Fri Oct 12 00:00:00 EDT 2001
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.jpg?time=20240507?time=20240507 "Phospho-Tau (Thr205) Antibody (44-738G) in WB")
