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FIGURE: 1 / 6
QSOX1 Antibody (PA5-106300) in ICC/IF
Immunofluorescent analysis of QSOX1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and QSOX1 polyclonal antibody (Product # PA5-106300) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-106300
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human QSOX1(Accession O00391), corresponding to amino acid residues L375-H425.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853977
Product Specific Information
Antibody detects endogenous levels of total Quiescin Q6.
Target Information
The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia and appears to protect cells against oxidative stress-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FAD-dependent sulfhydryl oxidase-2; hQSOX; mSOx; Quiescin Q6; quiescin Q6 sulfhydryl oxidase 1; RP11-502H18.3; rQSOX; Skin sulfhydryl oxidase; SOx-2; Sulfhydryl oxidase 1; testis tissue sperm-binding protein Li 62n; thiol oxidase 1
Gene Aliases: 1300003H02Rik; Q6; QSCN6; QSOX; QSOX1; rSOx; SOx; Sox-2; Sox2; UNQ2520/PRO6013
UniProt ID: (Human) O00391, (Mouse) Q8BND5, (Rat) Q6IUU3
Entrez Gene ID: (Human) 5768, (Mouse) 104009, (Rat) 84491
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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