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Product Details
MA5-45967
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4G10
Immunogen
Full length recombinant RAB1A protein
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
9.1mM sodium bicarbonate/PBS, pH 7.4, with 581mM DMSO, 123mM ethanolamine
Contains
no preservative
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2932421
Product Specific Information
A 1:1,000 dilution of MA5-45967 was sufficient for detection of RAB1A in 10 µg (A549, MEF); 20 µg (Mouse Brain) lysates by ECL immunoblot analysis.
Detects approximately 23 kDa. Cross-reacts with RAB1B and RAB1C.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZP564B163; GTP binding protein Rab1a; Rab GTPase YPT1 homolog; RAB1, member RAS oncogene family; Ras-related protein Rab-1A; ras-related YPT1 protein; YPT1-related protein
Gene Aliases: Gtbp; mKIAA3012; Rab-1; RAB1; RAB1A; YPT1
UniProt ID: (Human) P62820, (Mouse) P62821
Entrez Gene ID: (Human) 5861, (Mouse) 19324
autophagosome assembly
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
endocytosis
autophagy
Golgi organization
small GTPase mediated signal transduction
vesicle-mediated transport
cell migration
virion assembly
growth hormone secretion
melanosome transport
substrate adhesion-dependent cell spreading
cilium assembly
defense response to bacterium
vesicle transport along microtubule
COPII vesicle coating
interleukin-8 secretion
cargo loading into COPII-coated vesicle
establishment of endothelial intestinal barrier
cell-cell adhesion
positive regulation of glycoprotein metabolic process
transport
intracellular protein transport
protein transport
Rab protein signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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