Proteintech

RBAP48 Polyclonal Antibody

RBAP48 Antibody in Immunocytochemistry (ICC/IF)

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RBAP48 Antibody (20364-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 20364-1-AP (RBAP48 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

RBAP48 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RBAP48 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

20364-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 10 publications 10 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The antibody is specific to RBBP4.

Target Information

RbAp48-11G10 recognizes full length RbAp48, a 48 kDa nuclear protein first isolated by its ability to interact with the carboxyl-terminus of the retinoblastoma protein (Rb). It is a member of the WD (Trp-Asp) repeat family of proteins. RbAp48 is one of the three subunits of CAF-1, can bind to histone H4 and is a subunit of human histone deacetylase HD1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Photoaffinity Labeling-Based Chemoproteomic Strategy Reveals RBBP4 as a Cellular Target of Protopanaxadiol against Colorectal Cancer Cells.

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ZIC2-dependent OCT4 activation drives self-renewal of human liver cancer stem cells.

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Bioinformatics

Protein Aliases: CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; Chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; Histone-binding protein RBBP4; MSI1 protein homolog; Nucleosome-remodeling factor subunit RBAP48; RBBP-4; retinoblastoma binding protein 4; Retinoblastoma-binding protein 4; Retinoblastoma-binding protein p48

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Gene Aliases: lin-53; mRbAp48; NURF55; RBAP48; RBBP4

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UniProt ID: (Human) Q09028, (Mouse) Q60972

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Entrez Gene ID: (Human) 5928, (Mouse) 19646

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Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding histone deacetylase activity protein binding DNA-dependent ATPase activity nucleosomal DNA binding histone binding histone deacetylase binding

Process(es)

DNA replication DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated cell cycle negative regulation of cell proliferation histone deacetylation chromatin assembly CENP-A containing nucleosome assembly ATP-dependent chromatin remodeling negative regulation of gene expression, epigenetic regulation of cell cycle regulation of signal transduction by p53 class mediator chromatin modification

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RBAP48 Polyclonal Antibody

RBAP48 Antibody (20364-1-AP) in ICC/IF

Product Details

20364-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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