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REEP2 Polyclonal Antibody

REEP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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REEP2 Antibody (15684-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded Mouse brain tissue slide using (Product # 15684-1-AP) REEP2 antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

REEP2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

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Product Details

15684-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 10 publications 10 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

REEP2 Fusion Protein Ag8186 (70-252 aa encoded by BC006218)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: IAFVIWLLS PYTKGSSVLY RKFVHPTLSN KEKEIDEYIT QARDKSYETM MRVGKRGLNL AANAAVTAAA KGVLSEKLRS FSMQDLTLIR DEDALPLQRP DGRLRPSPGS LLDTIEDLGD DPALSLRSST NPADSRTEAS EDDMGDKAPK RAKPIKKAPK AEPLASKTLK TRPKKKTSGG GDSA (70-252 aa encoded by BC006218)

Target Information

Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Chidamide suppresses adipogenic differentiation of bone marrow derived mesenchymal stem cells via increasing REEP2 expression.

iScience

Zhang X,Liu L,Liu X,Huang Q,Liu L,Liu H,Ren S,Wei P,Cheng P,Yao M,Song W,Zhang H,Chen M

Fri Mar 17 00:00:00 EDT 2023

Pathological characteristics of axons and proteome patterns in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency.

Research square

Le W,Wang P,Al-Nusaif M,Zhang J,Yang H,Yang Y,Kim K,Li S,Liu C,Cai H

Thu May 18 00:00:00 EDT 2023

Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.

Nature

Foronda H,Fu Y,Covarrubias-Pinto A,Bocker HT,González A,Seemann E,Franzka P,Bock A,Bhaskara RM,Liebmann L,Hoffmann ME,Katona I,Koch N,Weis J,Kurth I,Gleeson JG,Reggiori F,Hummer G,Kessels MM,Qualmann B,Mari M,Dikić I,Hübner CA

Thu Jun 01 00:00:00 EDT 2023

ER proteins decipher the tubulin code to regulate organelle distribution.

Nature

Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C

Sat Jan 01 00:00:00 EST 2022

Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.

Human molecular genetics

Zhu PP,Hung HF,Batchenkova N,Nixon-Abell J,Henderson J,Zheng P,Renvoisé B,Pang S,Xu CS,Saalfeld S,Funke J,Xie Y,Svara F,Hess HF,Blackstone C

Tue Aug 23 00:00:00 EDT 2022

Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains.

Neurobiology of aging

Sharoar MG,Zhou J,Benoit M,He W,Yan R

Mon Nov 01 00:00:00 EDT 2021

Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains.

Neurobiology of aging

Sharoar MG,Zhou J,Benoit M,He W,Yan R

Mon Nov 01 00:00:00 EDT 2021

Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.

Cell metabolism

Wang X,Wang H,Xu B,Huang D,Nie C,Pu L,Zajac GJM,Yan H,Zhao J,Shi F,Emmer BT,Lu J,Wang R,Dong X,Dai J,Zhou W,Wang C,Gao G,Wang Y,Willer C,Lu X,Zhu Y,Chen XW

Tue Feb 02 00:00:00 EST 2021

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.

Current biology : CB

Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J

Mon Mar 04 00:00:00 EST 2019

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 EDT 2018

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 EDT 2018

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 EDT 2018

Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.

Molecular psychiatry

Sharoar MG,Shi Q,Ge Y,He W,Hu X,Perry G,Zhu X,Yan R

Thu Sep 01 00:00:00 EDT 2016

Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.

Molecular psychiatry

Sharoar MG,Shi Q,Ge Y,He W,Hu X,Perry G,Zhu X,Yan R

Thu Sep 01 00:00:00 EDT 2016

Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.

Human molecular genetics

Renvoisé B,Malone B,Falgairolle M,Munasinghe J,Stadler J,Sibilla C,Park SH,Blackstone C

Thu Dec 01 00:00:00 EST 2016

Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.

Human molecular genetics

Renvoisé B,Malone B,Falgairolle M,Munasinghe J,Stadler J,Sibilla C,Park SH,Blackstone C

Thu Dec 01 00:00:00 EST 2016

REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues.

Brain research

Hurt CM,Björk S,Ho VK,Gilsbach R,Hein L,Angelotti T

Thu Jan 30 00:00:00 EST 2014

REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues.

Brain research

Hurt CM,Björk S,Ho VK,Gilsbach R,Hein L,Angelotti T

Thu Jan 30 00:00:00 EST 2014

REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues.

Brain research

Hurt CM,Björk S,Ho VK,Gilsbach R,Hein L,Angelotti T

Thu Jan 30 00:00:00 EST 2014

Bioinformatics

Protein Aliases: C2orf19; LOC682105; Receptor expression-enhancing protein 2

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Gene Aliases: C5orf19; REEP2; SGC32445; SPG72; Yip2d

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UniProt ID: (Human) Q9BRK0, (Mouse) Q8VCD6

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Entrez Gene ID: (Human) 51308, (Rat) 682105, (Mouse) 225362

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Function(s)

taste receptor binding membrane traffic protein

Process(es)

positive regulation of defense response to virus by host regulation of intracellular transport protein transport into membrane raft sensory perception of bitter taste sensory perception of sweet taste endoplasmic reticulum tubular network organization xenophagy

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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REEP2 Polyclonal Antibody

REEP2 Antibody (15684-1-AP) in IHC (P)

Product Details

15684-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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