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Product Details
PA5-34173
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from C-terminus of human RXFP2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551526
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Gibbon, Rabbit (94%) Monkey, Rat, Panda, Bovine, Dog, Horse (89%) Mouse (83%).
Target Information
The activity of this relaxin receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP and may also be a receptor for Leydig insulin-like peptide. Expressed in embryonic and adult gonads of males and females, as well in male gubernarculum and in brain. Not detected in kidney, spleen and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein coupled receptor affecting testicular descent; G protein-coupled receptor 106; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; leucine-rich repeat-containing G protein-coupled receptor 8; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2; Relaxin receptor 2; relaxin/insulin-like family peptide receptor 2
Gene Aliases: GPR106; GREAT; INSL3R; LGR8; LGR8.1; RXFP2; RXFPR2
UniProt ID: (Human) Q8WXD0, (Mouse) Q91ZZ5
Entrez Gene ID: (Human) 122042, (Mouse) 140498
oocyte maturation
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
male gonad development
positive regulation of cAMP biosynthetic process
negative regulation of apoptotic process
signal transduction
G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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