Proteintech

Recoverin Polyclonal Antibody

Recoverin Antibody in Immunocytochemistry (ICC/IF)

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Recoverin Antibody (10073-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed Y79 cells using Recoverin antibody (Product # 10073-1-AP) at dilution of 1:20 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

10073-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:25

View 7 publications 7 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recoverin Fusion Protein Ag0119 (7-166 aa encoded by BC001720)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: GALSKEILE ELQLNTKFSE EELCSWYQSF LKDCPTGRIT QQQFQSIYAK FFPDTDPKAY AQHVFRSFDS NLDGTLDFKE YVIALHMTTA GKTNQKLEWA FSLYDVDGNG TISKNEVLEI VMAIFKMITP EDVKLLPDDE NTPEKRAEKI WKYFGKNDDD K (7-166 aa encoded by BC001720)

Target Information

Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy.

Communications biology

Watari K,Yamasaki S,Tu HY,Shikamura M,Kamei T,Adachi H,Tochitani T,Kita Y,Nakamura A,Ueyama K,Ono K,Morinaga C,Matsuyama T,Sho J,Nakamura M,Fujiwara M,Hori Y,Tanabe A,Hirai R,Terai O,Ohno O,Ohara H,Hayama T,Ikeda A,Nukaya D,Matsushita K,Takahashi M,Kishino A,Kimura T,Kawamata S,Mandai M,Kuwahara A

Fri Feb 10 00:00:00 EST 2023

Microglia activation and neuronal alterations in retinas from COVID-19 patients: correlation with clinical parameters.

Eye and vision (London, England)

Albertos-Arranz H,Martínez-Gil N,Sánchez-Sáez X,Noailles A,Monferrer Adsuara C,Remolí Sargues L,Pérez-Santonja JJ,Lax P,Calvo Andrés R,Cuenca N

Wed Mar 01 00:00:00 EST 2023

Legumain affects the PI3K/AKT tumor progression pathway in retinoblastoma.

Experimental eye research

Tang Q,Xu F,Lin J,Zhang C,Liu X,Dong L,Zhao J,Zhu L,Lin T

Tue Nov 01 00:00:00 EDT 2022

Addition of Chk1 inhibitor and BMP4 cooperatively promotes retinal tissue formation in self-organizing human pluripotent stem cell differentiation culture.

Regenerative therapy

Yamasaki S,Kuwahara A,Kishino A,Kimura T,Takahashi M,Mandai M

Tue Mar 01 00:00:00 EST 2022

One-step induction of photoreceptor-like cells from human iPSCs by delivering transcription factors.

iScience

Otsuka Y,Imamura K,Oishi A,Kondo T,Suga M,Yada Y,Shibukawa R,Okanishi Y,Sagara Y,Tsukita K,Tsujikawa A,Inoue H

Fri Apr 15 00:00:00 EDT 2022

A Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation.

iScience

Yamasaki S,Tu HY,Matsuyama T,Horiuchi M,Hashiguchi T,Sho J,Kuwahara A,Kishino A,Kimura T,Takahashi M,Mandai M

Fri Jan 21 00:00:00 EST 2022

Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease.

iScience

Zhang J,Gao F,Ma Y,Xue T,Shen Y

Fri Nov 19 00:00:00 EST 2021

Microglia dynamics in retinitis pigmentosa model: formation of fundus whitening and autofluorescence as an indicator of activity of retinal degeneration.

Scientific reports

Makabe K,Sugita S,Mandai M,Futatsugi Y,Takahashi M

Mon Sep 07 00:00:00 EDT 2020

Preconditioning the Initial State of Feeder-free Human Pluripotent Stem Cells Promotes Self-formation of Three-dimensional Retinal Tissue.

Scientific reports

Kuwahara A,Yamasaki S,Mandai M,Watari K,Matsushita K,Fujiwara M,Hori Y,Hiramine Y,Nukaya D,Iwata M,Kishino A,Takahashi M,Sasai Y,Kimura T

Thu Dec 12 00:00:00 EST 2019

Transplanted olfactory ensheathing cells reduce retinal degeneration in Royal College of Surgeons rats.

Current eye research

Huo SJ,Li YC,Xie J,Li Y,Raisman G,Zeng YX,He JR,Weng CH,Yin ZQ

Wed Aug 01 00:00:00 EDT 2012

Transplanted olfactory ensheathing cells reduce retinal degeneration in Royal College of Surgeons rats.

Current eye research

Huo SJ,Li YC,Xie J,Li Y,Raisman G,Zeng YX,He JR,Weng CH,Yin ZQ

Wed Aug 01 00:00:00 EDT 2012

Evaluation of canine serum for the presence of antiretinal autoantibodies in sudden acquired retinal degeneration syndrome.

Veterinary ophthalmology

Keller RL,Kania SA,Hendrix DV,Ward DA,Abrams K

Tue Jun 27 00:00:00 EDT 2006

Evaluation of canine serum for the presence of antiretinal autoantibodies in sudden acquired retinal degeneration syndrome.

Veterinary ophthalmology

Keller RL,Kania SA,Hendrix DV,Ward DA,Abrams K

Tue Jun 27 00:00:00 EDT 2006

Differentiation of marrow stromal cells into photoreceptors in the rat eye.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Kicic A,Shen WY,Wilson AS,Constable IJ,Robertson T,Rakoczy PE

Wed Aug 27 00:00:00 EDT 2003

Differentiation of marrow stromal cells into photoreceptors in the rat eye.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Kicic A,Shen WY,Wilson AS,Constable IJ,Robertson T,Rakoczy PE

Wed Aug 27 00:00:00 EDT 2003

Bioinformatics

Protein Aliases: 23 kDa photoreceptor cell-specific protein; cancer associated retinopathy antigen; cancer associated retinopathy protein; Cancer-associated retinopathy protein; guanylate cyclase activator; Protein CAR; Recoverin

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Gene Aliases: CAR; RCV1; RCVRN; S-modulin

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UniProt ID: (Human) P35243, (Mouse) P34057

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Entrez Gene ID: (Human) 5957, (Mouse) 19674, (Rat) 140936

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Function(s)

calcium ion binding calcium sensitive guanylate cyclase activator activity metal ion binding

Process(es)

signal transduction visual perception phototransduction positive regulation of guanylate cyclase activity regulation of calcium ion transport response to stimulus

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Recoverin Polyclonal Antibody

Recoverin Antibody (10073-1-AP) in ICC/IF

Product Details

10073-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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