Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: MKLLTGLVFC SLVLGVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY DAAKRGPGGA WAAEVISDAR ENIQRFFGHG AEDSLADQAA
The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; SAA rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging.
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Protein Aliases: amyloid a; MGC111216; serum amyloid A 2; Serum amyloid A-1 protein; Serum amyloid A1 protein; Serum Amyloid-A
Gene Aliases: Saa-1; Saa1; Saa2
UniProt ID: (Mouse) P05366
Entrez Gene ID: (Mouse) 20208
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