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Invitrogen
SSTR2 Recombinant Rabbit Monoclonal Antibody (11H21L13)
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 6
SSTR2 Antibody (704011) in ICC/IF
HEK-293 cells stably transfected with SSTR2 were grown on poly-L-lysine-coated coverslips overnight. After 24 h, cells were treated with 1 µM Somatostatin-14 (SRIF) and then fixed with 4% paraformaldehyde and 0.2% picric acid in phosphate buffer (pH 6.9) for 30 min at room temperature and washed several times with phosphate buffer. Specimens were permeabilized with ice-cold methanol and then incubated with Anti-SSTR2 Recombinant Rabbit Monoclonal Antibody (Product # 704011, 1:1000 dilution). Cells were then incubated with Alexa488-conjugat... View More
Product Details
704011
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
11H21L13
Immunogen
Peptides corresponding to residues 335-369 of Human SSTR2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2895896
Target Information
SSTR2 (somatostatin receptor 2) is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in the cerebrum and kidney. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The receptor is coupled via pertussis toxin sensitive G proteins to inhibit adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: somatostatin receptor; somatostatin receptor 2a; Somatostatin receptor type 2; SRIF-1; SS-2-R; SS2R; SSR2; SSTR2A
Gene Aliases: SSTR2
UniProt ID: (Human) P30874
Entrez Gene ID: (Human) 6752
regulation of muscle contraction
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
chemical synaptic transmission
spermatogenesis
response to nutrient
digestion
negative regulation of cell proliferation
cerebellum development
peristalsis
forebrain development
somatostatin signaling pathway
response to starvation
cellular response to glucocorticoid stimulus
cellular response to estradiol stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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