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Immunogen sequence: HSSTHVLGAA AEQFLGAVLC RGPSTEYGFY HDFFLGKERT IRGSELPVLE RICQELTAAA RPFRRLEASR DQLRQLFKDN PFKLHLIE
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 82%.
This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Threonine--tRNA ligase, mitochondrial; Threonyl-tRNA synthetase; threonyl-tRNA synthetase, mitochondrial; Threonyl-tRNA synthetase-like 1; ThrRS
Gene Aliases: 2610024N01Rik; AI429208; COXPD21; RGD1308283; TARS2; TARSL1; thrRS
UniProt ID: (Human) Q9BW92, (Mouse) Q3UQ84, (Rat) Q68FW7
Entrez Gene ID: (Human) 80222, (Mouse) 71807, (Rat) 310672
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