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Product Details
PA5-42827
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human UBD
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2610375
Product Specific Information
Peptide sequence: RSKTKVPVQD QVLLLGSKIL KPRRSLSSYG IDKEKTIHLT LKVVKPSDEE
Sequence homology: Cow: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 85%; Rat: 86%
Target Information
UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is not significantly overexpressed in cancers lacking a proinflammatory environment. Immunohistochemical studies demonstrated increased UBD expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Diubiquitin; UBD 3; Ubiquitin D; Ubiquitin-like protein FAT10
Gene Aliases: FAT10; GABBR1; UBD; UBD-3
UniProt ID: (Human) O15205
Entrez Gene ID: (Human) 10537
proteolysis
ubiquitin-dependent protein catabolic process
response to organonitrogen compound
protein ubiquitination
protein modification by small protein conjugation
response to interferon-gamma
response to tumor necrosis factor
myeloid dendritic cell differentiation
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
aggresome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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