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Product Details
TA505262
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI1G10
Immunogen
Full length human recombinant protein of human UBE2G2 produced in HEk293T cell.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2 ubiquitin-conjugating enzyme G2; Ubiquitin carrier protein G2; ubiquitin conjugating enzyme 7; ubiquitin conjugating enzyme E2G 2; ubiquitin conjugating enzyme G2; ubiquitin-conjugating enzyme 7 homolog; Ubiquitin-conjugating enzyme E2 G2; ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7); ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Ubiquitin-protein ligase G2
Gene Aliases: 1110003O05Rik; D10Xrf369; UBC7; Ubc7p; UBE2G2
UniProt ID: (Human) P60604, (Mouse) P60605
Entrez Gene ID: (Human) 7327, (Dog) 611581, (Rat) 294331, (Mouse) 22213
ubiquitin-dependent protein catabolic process
protein N-linked glycosylation via asparagine
ER-associated ubiquitin-dependent protein catabolic process
cellular response to interferon-beta
cellular protein catabolic process
protein K48-linked ubiquitination
negative regulation of retrograde protein transport, ER to cytosol
protein polyubiquitination
protein ubiquitination
Performance Guarantee
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