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Product Details
PA5-76202
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human UBE2T.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2719929
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell proliferation-inducing gene 50 protein; E2 ubiquitin-conjugating enzyme T; HSPC150 protein similar to ubiquitin-conjugating enzyme; Ubiquitin carrier protein T; ubiquitin conjugating enzyme E2T; Ubiquitin-conjugating enzyme E2 T; ubiquitin-conjugating enzyme E2T (putative); Ubiquitin-protein ligase T
Gene Aliases: 2700084L22Rik; C80607; FANCT; HSPC150; PIG50; RGD1310816; UBE2T
UniProt ID: (Human) Q9NPD8, (Mouse) Q9CQ37
Entrez Gene ID: (Human) 29089, (Rat) 360847, (Mouse) 67196
DNA repair
protein monoubiquitination
cellular response to DNA damage stimulus
protein K29-linked ubiquitination
interstrand cross-link repair
protein K27-linked ubiquitination
protein autoubiquitination
protein K63-linked ubiquitination
protein K48-linked ubiquitination
protein K11-linked ubiquitination
protein K6-linked ubiquitination
protein polyubiquitination
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