Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: IEDAVEHEQ KKSSKRTLPA DYGDSLAKRG SCSPWPDAPT AYVNNSPSPA PTFTSPQQST CSVPDSNSSS PNHQGDGASQ TSGEQIQPSA TIQETQQWLL KNRFSSYTRL FSNFSGADLL KLTKEDLVQI CGAADGIRLY NSLKSRSVRP RLTIYVCREQ PSSTVLQGQQ QAASSASENG SGAPYVYHAI YLEEMIASEV ARKLALVFNI PLHQINQVYR QGPTGIHILV SDQMVQNFQD ESCFLFSTVK AESSDGIHII LK (280-540 aa encoded by BC047235)
UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NF2d9; Nuclear factor 2d9; Transcription factor LBP-1; Upstream-binding protein 1
Gene Aliases: Cp2b; LBP-1a; LBP-1B; LBP1; LBP1A; LBP1B; NF2d9; RGD1564700; UBP1
UniProt ID: (Human) Q9NZI7, (Mouse) Q811S7
Entrez Gene ID: (Human) 7342, (Rat) 301038, (Mouse) 22221
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