Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: GASQTSGEQI QPSATIQETQ QWLLKNRFSS YTRLFSNFSG ADLLKLTKED
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Guinea Pig: 92%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 92%
UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Transcription factor LBP-1; Upstream-binding protein 1
Gene Aliases: LBP-1a; LBP-1B; LBP1; LBP1A; LBP1B; UBP1
UniProt ID: (Human) Q9NZI7
Entrez Gene ID: (Human) 7342
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