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Product Details
H00091544-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1B10
Immunogen
UBXN11 (NP_663320.1, 311 a.a. approximately 409 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: QGEVIDIRGP IRDTLQNCCP LPARIQEIVV ETPTLAAERE RSQESPNTPA PPLSMLRIKS ENGEQAFLLM MQPDNTIGDV RALLAQARVM DASAFEIFS
Target Information
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Colorectal tumor-associated antigen COA-1; colorectal tumor-associated antigen-1; Socius; UBX domain-containing protein 11; UBX domain-containing protein 5
Gene Aliases: COA-1; PP2243; SOC; SOCI; UBXD5; UBXN11
UniProt ID: (Human) Q63HM6
Entrez Gene ID: (Human) 91544
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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