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Product Details
PA5-51151
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein of human UGT1A10
Conjugate
Form
Liquid
Concentration
3.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2636599
Product Specific Information
The antibody detects endogenous levels of total UGT1A10 protein.
Target Information
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: UDP glucuronosyltransferase 1 family, polypeptide A10; UDP glycosyltransferase 1 family polypeptide A13; UDP glycosyltransferase 1 family, polypeptide A10; UDP-glucuronosyltransferase 1-10; UDP-glucuronosyltransferase 1-7C; UDP-glucuronosyltransferase 1-J; UDP-glucuronosyltransferase 1A10; UDP-glucuronosyltransferase 1A7; UDP-glucuronosyltransferase 1A7C; UDPGT 1-10; UDPGT 1-7C; UGT-1J; UGT1*7C; UGT1-07C; UGT1.7C; UGT1A10; UGT1A7
Gene Aliases: A10'; A13; GNT1; UDPGT; UGT-1J; UGT1; UGT1-10; UGT1.10; UGT1A10; Ugt1a13; Ugt1a7; Ugt1a7c; UGT1J
UniProt ID: (Human) Q9HAW8, (Mouse) Q6ZQM8
Entrez Gene ID: (Human) 54575, (Mouse) 394430, (Mouse) 394432
retinoic acid binding
protein kinase C binding
glucuronosyltransferase activity
protein homodimerization activity
protein heterodimerization activity
enzyme inhibitor activity
steroid binding
fatty acid binding
drug binding
enzyme binding
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
glycosyltransferase
flavonoid biosynthetic process
flavone metabolic process
cellular glucuronidation
flavonoid glucuronidation
xenobiotic glucuronidation
cellular response to hormone stimulus
negative regulation of catalytic activity
estrogen catabolic process
metabolic process
aromatic compound catabolic process
coumarin catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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