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Product Details
OSR00333W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 100-150 of human UNC119 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: UNC119.
Target Information
This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hRG4; mRG4; POC7 centriolar protein homolog A; Protein unc-119 homolog A; retinal gene 4; Retinal protein 4; rRG4; unc-119 homolog
Gene Aliases: D11Bhm52; HRG4; IMD13; MRG4; POC7; POC7A; RG4; RRG4; Rtg4; UNC119; Unc119h; Uncl19
UniProt ID: (Human) Q13432, (Mouse) Q9Z2R6, (Rat) Q62885
Entrez Gene ID: (Human) 9094, (Mouse) 22248, (Rat) 29402
endocytosis
chemical synaptic transmission
visual perception
phototransduction
protein transport
lipoprotein transport
positive regulation of protein tyrosine kinase activity
negative regulation of clathrin-mediated endocytosis
negative regulation of caveolin-mediated endocytosis
transport
response to stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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