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Product Details
OSV00098W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 25-65 of human VAMP 3 conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: VAMP1, 2, 3.
Target Information
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CEB; Cellubrevin; synaptobrevin 1; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin II; Synaptobrevin-1; Synaptobrevin-2; Synaptobrevin-3; VAMP-1; VAMP-2; VAMP-3; vesicle-associated membrane 2; Vesicle-associated membrane protein (synaptobrevin 2); Vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1); Vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2); Vesicle-associated membrane protein 3
Gene Aliases: CEB; D130027G05Rik; lew; RATVAMPB; RATVAMPIR; SPAX1; SYB; Syb-1; Syb-2; SYB1; SYB2; SYB3; sybII; VAMP-1; VAMP-2; VAMP-3; VAMP1; VAMP2; VAMP3
UniProt ID: (Human) P23763, (Human) P63027, (Human) Q15836, (Mouse) Q62442, (Rat) Q63666, (Mouse) P63044, (Rat) P63045, (Mouse) P63024, (Rat) P63025
Entrez Gene ID: (Human) 6843, (Human) 6844, (Human) 9341, (Mouse) 22317, (Rat) 25624, (Mouse) 22318, (Rat) 24803, (Mouse) 22319, (Rat) 29528
positive regulation of receptor recycling
protein complex assembly
transport
vesicle fusion
protein transport
vesicle-mediated transport
calcium ion regulated exocytosis
substrate adhesion-dependent cell spreading
SNARE complex assembly
retrograde transport, endosome to Golgi
Golgi to plasma membrane protein transport
negative regulation of secretion by cell
exocytosis
response to glucose
synaptic vesicle exocytosis
regulation of exocytosis
regulation of calcium ion-dependent exocytosis
cellular response to insulin stimulus
eosinophil degranulation
long-term synaptic potentiation
regulation of vesicle-mediated transport
membrane fusion
positive regulation of intracellular protein transport
regulation of delayed rectifier potassium channel activity
neurotransmitter secretion
neutrophil degranulation
natural killer cell degranulation
mucus secretion
regulation of histamine secretion by mast cell
vesicle docking involved in exocytosis
positive regulation of immunoglobulin secretion
intracellular protein transport
post-Golgi vesicle-mediated transport
glutamate secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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