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Immunogen sequence: KSLAFHTMLT KGVGSDDGED ENRGDIPASI SLSEIDPLGQ GNDKLPFKTD TERSQLGESS VSYPNIIHID SENLSETVKE NSQEETPETT ASPIEYQDKL
Ventricular zone-expressed PH domain-containing protein homolog 1 (VEPH1), also known as KIAA1692 or Protein melted, is a 833 amino acid protein belonging to the MELT/VEPH family. VEPH1 is a peripheral membrane protein localized to the cytoplasmic side. VEPH1 has one PH domain which is required for the membrane targeting of the protein. The human gene encoding VEPH1 is 76% homologous to the Drosophila VEPH1 gene which encodes a protein that acts as a regulator of the insulin signaling pathway. It is thought that this role of VEPH1 is conserved across species. VEPH1 exists as three isoforms produced by alternative splicing.
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Protein Aliases: Protein melted; Protein melted homolog; ventricular zone expressed PH domain homolog 1; ventricular zone expressed PH domain-containing 1; Ventricular zone-expressed PH domain-containing protein 1; Ventricular zone-expressed PH domain-containing protein homolog 1
Gene Aliases: 2810471M23Rik; KIAA1692; MELT; VEPH; VEPH1
UniProt ID: (Human) Q14D04, (Mouse) A1A535
Entrez Gene ID: (Human) 79674, (Mouse) 72789
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