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FIGURE: 1 / 3
Recommended positive controls: U87-MG, SK-N-SH, IMR-32, SK-N-AS, mouse heart.
Predicted reactivity: Mouse (91%), Rat (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Ventricular zone-expressed PH domain-containing protein homolog 1 (VEPH1), also known as KIAA1692 or Protein melted, is a 833 amino acid protein belonging to the MELT/VEPH family. VEPH1 is a peripheral membrane protein localized to the cytoplasmic side. VEPH1 has one PH domain which is required for the membrane targeting of the protein. The human gene encoding VEPH1 is 76% homologous to the Drosophila VEPH1 gene which encodes a protein that acts as a regulator of the insulin signaling pathway. It is thought that this role of VEPH1 is conserved across species. VEPH1 exists as three isoforms produced by alternative splicing.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Protein melted; Protein melted homolog; ventricular zone expressed PH domain homolog 1; ventricular zone expressed PH domain-containing 1; Ventricular zone-expressed PH domain-containing protein 1; Ventricular zone-expressed PH domain-containing protein homolog 1
Gene Aliases: 2810471M23Rik; KIAA1692; MELT; VEPH; VEPH1
UniProt ID: (Human) Q14D04, (Mouse) A1A535
Entrez Gene ID: (Human) 79674, (Mouse) 72789
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