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Product Details
MA5-24790
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6A6
Immunogen
Synthetic peptide corresponding to the C-terminus of human VLDL Receptor.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2717263
Target Information
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ35024; non O-glycosylated VLDL-R; Very low-density lipoprotein receptor; VLDL receptor; VLDL-R
Gene Aliases: AA408956; AI451093; AW047288; CAMRQ1; CARMQ1; CHRMQ1; VLDL-R; VLDLR; VLDLRCH
UniProt ID: (Human) P98155, (Mouse) P98156
Entrez Gene ID: (Bovine) 282123, (Human) 7436, (Mouse) 22359, (Rat) 25696
glycoprotein binding
low-density lipoprotein receptor activity
calcium ion binding
protein binding
very-low-density lipoprotein particle receptor activity
apolipoprotein binding
very-low-density lipoprotein particle binding
glycoprotein transporter activity
reelin receptor activity
calcium-dependent protein binding
protein tyrosine kinase activator activity
apolipoprotein
negative regulation of transcription from RNA polymerase II promoter
lipid transport
receptor-mediated endocytosis
signal transduction
nervous system development
heart development
response to nutrient
memory
cholesterol metabolic process
ventral spinal cord development
cerebral cortex development
cellular response to insulin stimulus
glycoprotein transport
very-low-density lipoprotein particle clearance
reelin-mediated signaling pathway
cellular response to glucose starvation
response to drug
positive regulation of protein kinase activity
dendrite morphogenesis
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to hypoxia
positive regulation of dendrite development
lipid metabolic process
transport
endocytosis
steroid metabolic process
response to hypoxia
cell surface receptor signaling pathway
response to hormone
response to lipopolysaccharide
positive regulation of protein tyrosine kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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