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Product Details
CF505824
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI1F4
Immunogen
Full length human recombinant protein of human VTI1A produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SNARE Vti1a-beta protein; vesicle transport through interaction with t-SNAREs 1 homolog; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport v-SNARE protein Vti1-like 2; Vti1-rp2
Gene Aliases: 1110014F16Rik; 1110018K19Rik; 4921537J05Rik; MMDS3; MVti1; MVti1a; Vti1; Vti1-rp2; VTI1A; Vti1l2; VTI1RP2
UniProt ID: (Human) Q96AJ9, (Mouse) O89116, (Rat) Q9JI51
Entrez Gene ID: (Dog) 100685447, (Human) 143187, (Mouse) 53611, (Rat) 65277
protein targeting to vacuole
ER to Golgi vesicle-mediated transport
intra-Golgi vesicle-mediated transport
Golgi to vacuole transport
autophagy
retrograde transport, endosome to Golgi
vesicle fusion with Golgi apparatus
voluntary musculoskeletal movement
Golgi ribbon formation
transport
intracellular protein transport
protein transport
vesicle-mediated transport
membrane fusion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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