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Product Details
66398-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig,
Rabbit
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1D2C8
Immunogen
VTN Fusion Protein Ag8443 (126-478 aa encoded by BC005046)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EVGASKPEG IDSRPETLHP GRPQPPAEEE LCSGKPFDAF TDLKNGSLFA FRGQYCYELD EKAVRPGYPK LIRDVWGIEG PIDAAFTRIN CQGKTYLFKG SQYWRFEDGV LDPDYPRNIS DGFDGIPDNV DAALALPAHS YSGRERVYFF KGKQYWEYQF QHQPSQEECE GSSLSAVFEH FAMMQRDSWE DIFELLFWGR TSAGTRQPQF ISRDWHGVPG QVDAAMAGRI YISGMAPRPS LAKKQRFRHR NRKGYRSQRG HSRGRNQNSR RPSRAMWLSL FSSEESNLGA NNYDDYRMDW LVPATCEPIQ SVFFFSGDKY YRVNLRTRRV DTVDPPYPRS IAQYWLGCPA PGHL (126-478 aa encoded by B C005046)
Target Information
VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: complement S-protein; epibolin; Glycoprotein 66; S-protein; serum spreading factor; Serum-spreading factor; somatomedin B; V75; Vitronectin; VN
Gene Aliases: V75; VN; VNT; VTN
UniProt ID: (Human) P04004, (Pig) P48819, (Rabbit) P22458
Entrez Gene ID: (Human) 7448, (Pig) 397192, (Rabbit) 100009128
receptor-mediated endocytosis
immune response
cell adhesion
cell-matrix adhesion
positive regulation of cell-substrate adhesion
negative regulation of endopeptidase activity
positive regulation of smooth muscle cell migration
negative regulation of blood coagulation
extracellular matrix organization
regulation of complement activation
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein binding
cell adhesion mediated by integrin
endodermal cell differentiation
positive regulation of receptor-mediated endocytosis
oligodendrocyte differentiation
positive regulation of peptidyl-tyrosine phosphorylation
smooth muscle cell-matrix adhesion
positive regulation of wound healing
endocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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