Proteintech

Vitronectin Polyclonal Antibody

Vitronectin Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

Vitronectin Antibody (15833-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed NIH/3T3 cells using 15833-1-AP (Vitronectin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Vitronectin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Vitronectin Antibody in Western Blot (WB)

Product Image Gallery

Product Details

15833-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 11 publications 11 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 5 publications 5 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Vitronectin Fusion Protein Ag8443 (126-478 aa encoded by BC005046)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EVGASKPEG IDSRPETLHP GRPQPPAEEE LCSGKPFDAF TDLKNGSLFA FRGQYCYELD EKAVRPGYPK LIRDVWGIEG PIDAAFTRIN CQGKTYLFKG SQYWRFEDGV LDPDYPRNIS DGFDGIPDNV DAALALPAHS YSGRERVYFF KGKQYWEYQF QHQPSQEECE GSSLSAVFEH FAMMQRDSWE DIFELLFWGR TSAGTRQPQF ISRDWHGVPG QVDAAMAGRI YISGMAPRPS LAKKQRFRHR NRKGYRSQRG HSRGRNQNSR RPSRAMWLSL FSSEESNLGA NNYDDYRMDW LVPATCEPIQ SVFFFSGDKY YRVNLRTRRV DTVDPPYPRS IAQYWLGCPA PGHL (126-478 aa encoded by B C005046)

Target Information

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Binding of serum-derived amyloid-associated proteins to amyloid fibrils.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

Misumi Y,Tabata Y,Tasaki M,Obayashi K,Yamakawa S,Nomura T,Ueda M

Wed Mar 01 00:00:00 EST 2023

The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome.

BMC genomics

Zhao B,Wu C,Sammad A,Ma Z,Suo L,Wu Y,Fu X

Mon Mar 07 00:00:00 EST 2022

Isolation, culture, and cryosectioning of primary porcine retinal pigment epithelium on transwell cell culture inserts.

STAR protocols

Hood EMS,Curcio CA,Lipinski D

Fri Dec 16 00:00:00 EST 2022

Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.

Brain pathology (Zurich, Switzerland)

Wang H,Yang H,Shi Y,Xiao Y,Yin Y,Jiang B,Ren H,Chen W,Xue Q,Xu X

Wed Sep 01 00:00:00 EDT 2021

Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.

Brain pathology (Zurich, Switzerland)

Wang H,Yang H,Shi Y,Xiao Y,Yin Y,Jiang B,Ren H,Chen W,Xue Q,Xu X

Wed Sep 01 00:00:00 EDT 2021

The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.

Malaria journal

Tougan T,Edula JR,Morita M,Takashima E,Honma H,Tsuboi T,Horii T

Wed Apr 15 00:00:00 EDT 2020

The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.

Malaria journal

Tougan T,Edula JR,Morita M,Takashima E,Honma H,Tsuboi T,Horii T

Wed Apr 15 00:00:00 EDT 2020

Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.

Journal of cellular physiology

Wang H,Ning T,Song C,Luo X,Xu S,Zhang X,Deng Z,Ma D,Wu B

Thu Aug 01 00:00:00 EDT 2019

Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.

Journal of cellular physiology

Wang H,Ning T,Song C,Luo X,Xu S,Zhang X,Deng Z,Ma D,Wu B

Thu Aug 01 00:00:00 EDT 2019

Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.

Journal of cellular physiology

Wang H,Ning T,Song C,Luo X,Xu S,Zhang X,Deng Z,Ma D,Wu B

Thu Aug 01 00:00:00 EDT 2019

Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.

Journal of cellular physiology

Wang H,Ning T,Song C,Luo X,Xu S,Zhang X,Deng Z,Ma D,Wu B

Thu Aug 01 00:00:00 EDT 2019

Induction of migration of periodontal ligament cells by selective regulation of integrin subunits.

Journal of cellular and molecular medicine

Kawamura M,Yamamoto T,Yamashiro K,Kochi S,Yoshihara-Hirata C,Ideguchi H,Aoyagi H,Omori K,Takashiba S

Fri Feb 01 00:00:00 EST 2019

Induction of migration of periodontal ligament cells by selective regulation of integrin subunits.

Journal of cellular and molecular medicine

Kawamura M,Yamamoto T,Yamashiro K,Kochi S,Yoshihara-Hirata C,Ideguchi H,Aoyagi H,Omori K,Takashiba S

Fri Feb 01 00:00:00 EST 2019

Induction of migration of periodontal ligament cells by selective regulation of integrin subunits.

Journal of cellular and molecular medicine

Kawamura M,Yamamoto T,Yamashiro K,Kochi S,Yoshihara-Hirata C,Ideguchi H,Aoyagi H,Omori K,Takashiba S

Fri Feb 01 00:00:00 EST 2019

Induction of migration of periodontal ligament cells by selective regulation of integrin subunits.

Journal of cellular and molecular medicine

Kawamura M,Yamamoto T,Yamashiro K,Kochi S,Yoshihara-Hirata C,Ideguchi H,Aoyagi H,Omori K,Takashiba S

Fri Feb 01 00:00:00 EST 2019

VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer.

BMC cancer

Lian L,Li XL,Xu MD,Li XM,Wu MY,Zhang Y,Tao M,Li W,Shen XM,Zhou C,Jiang M

Thu Feb 28 00:00:00 EST 2019

VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer.

BMC cancer

Lian L,Li XL,Xu MD,Li XM,Wu MY,Zhang Y,Tao M,Li W,Shen XM,Zhou C,Jiang M

Thu Feb 28 00:00:00 EST 2019

Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model.

Acta biomaterialia

Ishiguro H,Kaito T,Yarimitsu S,Hashimoto K,Okada R,Kushioka J,Chijimatsu R,Takenaka S,Makino T,Sakai Y,Moriguchi Y,Otsuru S,Hart DA,Fujie H,Nakamura N,Yoshikawa H

Fri Mar 15 00:00:00 EDT 2019

Characterization of Initial Cell Adhesion on Charged Polymer Substrates in Serum-Containing and Serum-Free Media.

Langmuir : the ACS journal of surfaces and colloids

Hoshiba T,Yoshikawa C,Sakakibara K

Tue Apr 03 00:00:00 EDT 2018

Characterization of Initial Cell Adhesion on Charged Polymer Substrates in Serum-Containing and Serum-Free Media.

Langmuir : the ACS journal of surfaces and colloids

Hoshiba T,Yoshikawa C,Sakakibara K

Tue Apr 03 00:00:00 EDT 2018

Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.

Scientific reports

Tougan T,Edula JR,Takashima E,Morita M,Shinohara M,Shinohara A,Tsuboi T,Horii T

Thu Mar 22 00:00:00 EDT 2018

Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.

Scientific reports

Tougan T,Edula JR,Takashima E,Morita M,Shinohara M,Shinohara A,Tsuboi T,Horii T

Thu Mar 22 00:00:00 EDT 2018

Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.

Scientific reports

Tougan T,Edula JR,Takashima E,Morita M,Shinohara M,Shinohara A,Tsuboi T,Horii T

Thu Mar 22 00:00:00 EDT 2018

Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.

Scientific reports

Tougan T,Edula JR,Takashima E,Morita M,Shinohara M,Shinohara A,Tsuboi T,Horii T

Thu Mar 22 00:00:00 EDT 2018

Surface changes of nanotopography by carbon ion implantation to enhance the biocompatibility of silicone rubber: an in vitro study of the optimum ion fluence and adsorbed protein.

Journal of materials science. Materials in medicine

Li X,Zhou X,Chen Y,Yu S,Chen X,Xia X,Shi X,Zhang Y,Fan D

Fri Sep 15 00:00:00 EDT 2017

Surface changes of nanotopography by carbon ion implantation to enhance the biocompatibility of silicone rubber: an in vitro study of the optimum ion fluence and adsorbed protein.

Journal of materials science. Materials in medicine

Li X,Zhou X,Chen Y,Yu S,Chen X,Xia X,Shi X,Zhang Y,Fan D

Fri Sep 15 00:00:00 EDT 2017

SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.

Proteomics

Zhang H,Wu P,Chen F,Hao Y,Lao Y,Ren L,Sun L,Sun W,Wei H,Chan DW,Jiang Y,He F

Mon Sep 01 00:00:00 EDT 2014

SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.

Proteomics

Zhang H,Wu P,Chen F,Hao Y,Lao Y,Ren L,Sun L,Sun W,Wei H,Chan DW,Jiang Y,He F

Mon Sep 01 00:00:00 EDT 2014

Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.

Molecular biology reports

Liu Z,Gao Y,Hao F,Lou X,Zhang X,Li Y,Wu D,Xiao T,Yang L,Li Q,Qiu X,Wang E

Sat Nov 01 00:00:00 EDT 2014

Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.

Molecular biology reports

Liu Z,Gao Y,Hao F,Lou X,Zhang X,Li Y,Wu D,Xiao T,Yang L,Li Q,Qiu X,Wang E

Sat Nov 01 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: complement S-protein; epibolin; S-protein; serum spreading factor; Serum-spreading factor; somatomedin B; V75; Vitronectin; VN

View more View less

Gene Aliases: Aa1018; AI256434; V75; VN; VNT; VTN

View more View less

UniProt ID: (Human) P04004, (Mouse) P29788

View more View less

Entrez Gene ID: (Human) 7448, (Rat) 29169, (Mouse) 22370

View more View less

Function(s)

scavenger receptor activity integrin binding protein binding heparin binding polysaccharide binding extracellular matrix binding collagen binding identical protein binding

Process(es)

receptor-mediated endocytosis immune response cell-matrix adhesion positive regulation of cell-substrate adhesion negative regulation of endopeptidase activity positive regulation of smooth muscle cell migration extracellular matrix organization positive regulation of protein binding cell adhesion mediated by integrin endodermal cell differentiation positive regulation of receptor-mediated endocytosis positive regulation of peptidyl-tyrosine phosphorylation smooth muscle cell-matrix adhesion cell adhesion negative regulation of blood coagulation regulation of complement activation positive regulation of vascular endothelial growth factor receptor signaling pathway oligodendrocyte differentiation positive regulation of wound healing protein polymerization liver regeneration

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

Vitronectin Polyclonal Antibody

Vitronectin Antibody (15833-1-AP) in ICC/IF

Product Details

15833-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!