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Invitrogen
Vitronectin Polyclonal Antibody
FIGURE: 1 / 9
Vitronectin Antibody (PA5-27909) in IHC (P)
Vitronectin Polyclonal Antibody detects Vitronectin protein by immunohistochemical analysis. Sample: Paraffin-embedded human lung cancer. Vitronectin stained by Vitronectin Polyclonal Antibody (Product # PA5-27909) diluted at 1:1,000. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-27909
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Dog,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 22 and 472 of Human Vitronectin
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545385
Product Specific Information
Recommended positive controls: HepG2 conditioned medium, mouse brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: complement S-protein; epibolin; S-protein; serum spreading factor; Serum-spreading factor; somatomedin B; V75; Vitronectin; VN
Gene Aliases: AI256434; V75; VN; VNT; VTN
UniProt ID: (Human) P04004, (Mouse) P29788
Entrez Gene ID: (Human) 7448, (Mouse) 22370
receptor-mediated endocytosis
immune response
cell adhesion
cell-matrix adhesion
positive regulation of cell-substrate adhesion
negative regulation of endopeptidase activity
positive regulation of smooth muscle cell migration
negative regulation of blood coagulation
extracellular matrix organization
regulation of complement activation
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein binding
cell adhesion mediated by integrin
endodermal cell differentiation
positive regulation of receptor-mediated endocytosis
oligodendrocyte differentiation
positive regulation of peptidyl-tyrosine phosphorylation
smooth muscle cell-matrix adhesion
positive regulation of wound healing
protein polymerization
liver regeneration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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