Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Vitronectin Monoclonal Antibody (347317)
.jpg?time=20240507 "Vitronectin Antibody in Immunohistochemistry (Frozen) (IHC (F))")
FIGURE: 1 / 1
Vitronectin Antibody (MA5-24083) in IHC (F)
Immunohistochemical analysis of Vitronectin was detected in immersion fixed frozen sections of fetal mouse brain using 10 µg/mL Rat Anti-mouse Vitronectin Monoclonal Antibody (Product # MA5-24083) overnight at 4 °C. Tissue was stained with a 557-conjugated Anti-Rat IgG Secondary Antibody (re and counterstained with DAPI (blue).
.jpg?time=20240507)
.jpg?time=20240507?time=20240507 "Vitronectin Antibody (MA5-24083) in IHC (F)")
Product Details
MA5-24083
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Rat
/ IgG2A
Class
Monoclonal
Type
Antibody
Clone
347317
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Vitronectin Asp20-Lys478
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609020
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human Vitronectin is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: S-protein; Serum-spreading factor; Vitronectin; VN
Gene Aliases: AI256434; Vn; Vtn
UniProt ID: (Mouse) P29788
Entrez Gene ID: (Mouse) 22370
immune response
cell adhesion
cell-matrix adhesion
positive regulation of cell-substrate adhesion
negative regulation of endopeptidase activity
positive regulation of smooth muscle cell migration
extracellular matrix organization
positive regulation of protein binding
cell adhesion mediated by integrin
endodermal cell differentiation
positive regulation of receptor-mediated endocytosis
positive regulation of peptidyl-tyrosine phosphorylation
protein polymerization
smooth muscle cell-matrix adhesion
liver regeneration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support