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Antibody detects endogenous levels of total WDR18.
WD repeat domain 18 (WDR18) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WD repeats are minimally conserved regions of approximately 40 amino acids that commonly form a tertiary propeller structure. WDR18 is a 432 amino acid protein that contains six WD repeats and is encoded by a gene located on human chromosome 19. WDR18 may play a role during development. The complex PELP1-TEX10-WDR18 is required for the maturation and nucleolar release of the large ribosomal subunit.
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Protein Aliases: Involved in Processing ITS2 3 homolog; WD repeat-containing protein 18
Gene Aliases: 2310012I10Rik; AU044733; AW122032; Ipi3; R32184_1; WDR18
UniProt ID: (Human) Q9BV38, (Rat) Q499N3, (Mouse) Q4VBE8
Entrez Gene ID: (Human) 57418, (Rat) 314617, (Mouse) 216156
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