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Positive test controls include: Mouse skeletal muscle, Rat lung.
Immunogen sequence: EPLMEKGHLD HEQVGSMGLV EMLHRSNLLA LVGGGSSPKF SEISVLIWDD AREGKDSKEK LVLEFTFTKP VLSVRMRHDK IVIVLKNRIY VYSFPDNPRK LFEFDTRDNP KGLC
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.
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Protein Aliases: WD repeat domain phosphoinositide-interacting protein 4; WD repeat domain X-linked 1; WD repeat domain, X-linked 1; WD repeat-containing protein 45; WIPI-4
Gene Aliases: C79260; DXImx38e; JM5; Sfc19; Wdr45; Wdrx1; WIPI-4; Wipi4
UniProt ID: (Rat) Q5U2Y0, (Mouse) Q91VM3
Entrez Gene ID: (Rat) 302559, (Mouse) 54636
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