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WIPF1/WIP Antibody (TA590158) in WB
Western blot analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Cat # PS100001, Left lane) or pCMV6-ENTRY WIPF1 (Cat # RC217601, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and blotted with anti-WIPF1(Cat # TA590158). Positive lysates [LY401163] (100 µg) and [LC401163] (20 µg) can be purchased separately from OriGene.
Product Details
TA590158
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DNA immunization. This antibody is specific for the Middle Region of the target protein.
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC111041; Protein PRPL-2; testicular tissue protein Li 226; WAS/WASL interacting protein family, member 1; WAS/WASL-interacting protein family member 1; WASP interacting protein; WASP-interacting protein; Wiskott-Aldrich syndrome protein interacting protein; Wiskott-Aldrich syndrome protein-interacting protein
Gene Aliases: AI115543; D2Ertd120e; PRPL-2; WAS2; WASPIP; WIP; WIPF1
UniProt ID: (Human) O43516, (Mouse) Q8K1I7
Entrez Gene ID: (Human) 7456, (Mouse) 215280
actin cortical patch assembly
protein complex assembly
endocytosis
actin polymerization or depolymerization
regulation of cell shape
actin filament-based movement
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of actin nucleation
actin cortical patch localization
response to other organism
actin cytoskeleton organization
positive regulation of protein export from nucleus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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