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Product Details
PA5-90227
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 59-138 of human XK (NP_0665691)
Conjugate
Form
Liquid
Concentration
2.00 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805970
Product Specific Information
Immunogen sequence: HRDLSRDRPL VLLLHLLQLG PLFRCFEVFC IYFQSGNNEE PYVSITKKRQ MPKNGLSEEI EKEVGQAEGK LITHRSAFSR; Positive Samples: mouse pancreas, rat pancreas; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
The XK protein is a membrane-bound protein associated with the endoplasmic reticulum (ER) and forms part of the ER membrane complex (EMC), which is critical for various cellular processes. This protein is involved in the insertion, folding, and assembly of membrane proteins in eukaryotic cells. The XK protein's role in the ER highlights its importance in maintaining proper cell function, as the ER is integral in protein synthesis, lipid metabolism, and calcium storage. Furthermore, the XK protein's involvement in these processes underscores its significance in cellular homeostasis and its potential contribution to pathologies when mutated or dysfunctional.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endoplasmic reticulum membrane adapter protein XK; Kell blood group precursor (McLeod phenotype); Kell blood group precursor (McLeod phenotype) homolog; Kell complex 37 kDa component; Kx antigen; McLeod syndrome gene homolog; Membrane transport protein XK; neuroacanthocytosis; neurocanthocytosis; X-linked Kx blood group (McLeod syndrome) homolog; XK homolog; XK, Kell blood group complex subunit (McLeod syndrome); XK-related protein 1
Gene Aliases: 1810038K19Rik; KX; MCLDS; NA; NAC; X1k; XK; Xkh; XKR1; XRG1
UniProt ID: (Human) P51811, (Mouse) Q9QXY7, (Rat) Q5GH61
Entrez Gene ID: (Human) 7504, (Mouse) 22439, (Rat) 497078
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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