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Product Details
67196-1-IG150UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1A12E7
Conjugate
Form
Liquid
Concentration
2.7 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
YES1 is a recombinant human protein kinase that is a member of the SRC family of non-receptor tyrosine kinases and is the cellular homolog of the Yamaguchi sarcoma virus oncogene. It is involved in the regulation of cell growth and survival, including roles in apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-Src; cellular yes-1 protein; EC 2.7.10.2; p61-Yes; Proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase YES; Tyrosine-protein kinase Yes; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; Yamagichi sarcoma viral (v-yes-1) oncogene homolog 1; Yamaguchi sarcoma oncogene; Yamaguchi sarcoma viral oncogene homolog 1; YES1 proto-oncogene, Src family tyrosine kinase
Gene Aliases: c-Yes; HsT441; p60c-yes; P61-YES; YES; YES1
UniProt ID: (Human) P07947
Entrez Gene ID: (Human) 7525, (Rat) 24884
transmembrane receptor protein tyrosine kinase signaling pathway
glucose transport
peptidyl-tyrosine phosphorylation
cell differentiation
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
positive regulation of peptidyl-tyrosine phosphorylation
cellular response to retinoic acid
cellular response to peptide hormone stimulus
cellular response to transforming growth factor beta stimulus
cellular protein modification process
T cell costimulation
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of vascular permeability
ephrin receptor signaling pathway
leukocyte migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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