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Invitrogen
alanyl-tRNA Synthetase Polyclonal Antibody
Product Details
PA5-83712
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human AARS. Recombinant protein control fragment (Product #RP-104790).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2790865
Product Specific Information
Immunogen sequence: EFTVKNAQVR GGYVLHIGTI YGDLKVGDQV WLFIDEPRRR PIMSNHTATH ILNFALRSVL GEADQKGSLV APDRLRFDFT AKGAMSTQQI KKAEEIANEM IEAAKAVYTQ DCP
Target Information
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E. coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AARS; alanine tRNA ligase 1, cytoplasmic; Alanine--tRNA ligase, cytoplasmic; Alanyl-tRNA synthetase; alanyl-tRNA synthetase, cytoplasmic; AlaRS; Protein lactyltransferase AARS1; Renal carcinoma antigen NY-REN-42
Gene Aliases: AARS; AARS1; CMT2N; EIEE29
UniProt ID: (Human) P49588
Entrez Gene ID: (Human) 16
hair follicle development
tRNA modification
tRNA aminoacylation for protein translation
alanyl-tRNA aminoacylation
regulation of translational fidelity
protein folding
tRNA processing
cerebellar Purkinje cell layer development
endoplasmic reticulum unfolded protein response
response to amino acid
negative regulation of neuron apoptotic process
neuromuscular process controlling balance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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