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gamma Tubulin Polyclonal Antibody

gamma Tubulin Antibody in Immunocytochemistry (ICC/IF)

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gamma Tubulin Antibody (15176-1-AP) in ICC/IF

Immunofluorescent analysis of (10% Formaldehyde) fixed MDCK cells using 15176-1-AP (gamma Tubulin antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

gamma Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma Tubulin Antibody in Western Blot (WB)

gamma Tubulin Antibody in Flow Cytometry (Flow)

gamma Tubulin Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

15176-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:200

View 11 publications 11 publications

Flow Cytometry (Flow)

Assay-dependent

Immunoprecipitation (IP)

0.5-4.0 µg

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

gamma Tubulin Fusion Protein Ag7070 (103-451 aa encoded by BC000619)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody can label the centrosome structure.

Immunogen sequence: NWASGFSQG EKIHEDIFDI IDREADGSDS LEGFVLCHSI AGGTGSGLGS YLLERLNDRY PKKLVQTYSV FPNQDEMSDV VVQPYNSLLT LKRLTQNADC VVVLDNTALN RIATDRLHIQ NPSFSQINQL VSTIMSASTT TLRYPGYMNN DLIGLIASLI PTPRLHFLMT GYTPLTTDQS VASVRKTTVL DVMRRLLQPK NVMVSTGRDR QTNHCYIAIL NIIQGEVDPT QVHKSLQRIR ERKLANFIPW GPASIQVALS RKSPYLPSAH RVSGLMMANH TSISSLFERT CRQYDKLRKR EAFLEQFRKE DMFKDNFDEM DTSREIVQQL IDEYHAATRP DYISWGTQEQ (103-451 aa encoded by BC000619)

Target Information

This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hypoxia-Inducible Factor-2alpha Affects the MEK/ERK Signaling Pathway via Primary Cilia in Connection with the Intraflagellar Transport Protein 88 Homolog.

Molecular and cellular biology

Leu T,Denda J,Wrobeln A,Fandrey J

Tue May 02 00:00:00 EDT 2023

GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca²⁺ nanoparticles underlies distinct gene therapy effect in ovarian cancer.

Journal of nanobiotechnology

Su L,Sun Z,Qi F,Su H,Qian L,Li J,Zuo L,Huang J,Yu Z,Li J,Chen Z,Zhang S

Wed Jul 20 00:00:00 EDT 2022

GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca²⁺ nanoparticles underlies distinct gene therapy effect in ovarian cancer.

Journal of nanobiotechnology

Su L,Sun Z,Qi F,Su H,Qian L,Li J,Zuo L,Huang J,Yu Z,Li J,Chen Z,Zhang S

Wed Jul 20 00:00:00 EDT 2022

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.

Nature communications

Mascibroda LG,Shboul M,Elrod ND,Colleaux L,Hamamy H,Huang KL,Peart N,Singh MK,Lee H,Merriman B,Jodoin JN,Sitaram P,Lee LA,Fathalla R,Al-Rawashdeh B,Ababneh O,El-Khateeb M,Escande-Beillard N,Nelson SF,Wu Y,Tong L,Kenney LJ,Roy S,Russell WK,Amiel J,Reversade B,Wagner EJ

Thu Oct 13 00:00:00 EDT 2022

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.

Nature communications

Thu Oct 13 00:00:00 EDT 2022

Screening of co-pathogenic genes of non-alcoholic fatty liver disease and hepatocellular carcinoma.

Frontiers in oncology

Chen T,Zhang S,Zhou D,Lu P,Mo X,Tamrakar R,Yang X

Tue Aug 30 00:00:00 EDT 2022

Whole-exome sequencing identified novel variants in CPLANE1 that causes oral-facial-digital syndrome ¿ by inducing primary cilia abnormality.

Journal of cellular and molecular medicine

Qian W,Liu X,Wang Z,Xu Y,Zhang J,Li H,Zhong Q,Li C,Zhu L,Zhou Z,Pan W

Wed Jun 01 00:00:00 EDT 2022

Subtype-Selective Positive Modulation of K_Ca2.3 Channels Increases Cilia Length.

ACS chemical biology

Nam YW,Pala R,El-Sayed NS,Larin-Henriquez D,Amirrad F,Yang G,Rahman MA,Orfali R,Downey M,Parang K,Nauli SM,Zhang M

Fri Aug 19 00:00:00 EDT 2022

Echinoderm Microtubule Associated Protein Like 1 Is Indispensable for Oocyte Spindle Assembly and Meiotic Progression in Mice.

Frontiers in cell and developmental biology

Yin H,Zhang T,Wang H,Hu X,Hou X,Fang X,Yin Y,Li H,Shi L,Su YQ

Tue Jun 15 00:00:00 EDT 2021

Echinoderm Microtubule Associated Protein Like 1 Is Indispensable for Oocyte Spindle Assembly and Meiotic Progression in Mice.

Frontiers in cell and developmental biology

Yin H,Zhang T,Wang H,Hu X,Hou X,Fang X,Yin Y,Li H,Shi L,Su YQ

Tue Jun 15 00:00:00 EDT 2021

LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton.

Frontiers in cell and developmental biology

Bozal-Basterra L,Gonzalez-Santamarta M,Muratore V,Martín-Martín N,Ercilla A,Rodríguez JA,Carracedo A,Sutherland JD,Barrio R

Wed Apr 21 00:00:00 EDT 2021

Down-regulation of Polo-like kinase 4 (PLK4) induces G1 arrest via activation of the p38/p53/p21 signaling pathway in bladder cancer.

FEBS open bio

Yang Z,Sun H,Ma W,Wu K,Peng G,Ou T,Wu S

Wed Sep 01 00:00:00 EDT 2021

LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome.

eLife

Bozal-Basterra L,Gonzalez-Santamarta M,Muratore V,Bermejo-Arteagabeitia A,Da Fonseca C,Barroso-Gomila O,Azkargorta M,Iloro I,Pampliega O,Andrade R,Martín-Martín N,Branon TC,Ting AY,Rodríguez JA,Carracedo A,Elortza F,Sutherland JD,Barrio R

Thu Jun 18 00:00:00 EDT 2020

Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts.

Scientific reports

Jühlen R,Martinelli V,Vinci C,Breckpot J,Fahrenkrog B

Mon Nov 09 00:00:00 EST 2020

Haploinsufficiency of GCP4 induces autophagy and leads to photoreceptor degeneration due to defective spindle assembly in retina.

Cell death and differentiation

Li Z,Li H,Xu X,Wang L,Liu B,Zheng W,Lian L,Song Y,Xia X,Hou L,Cheng H,Zhou R

Sat Feb 01 00:00:00 EST 2020

Nearly complete deletion of BubR1 causes microcephaly through shortened mitosis and massive cell death.

Human molecular genetics

Simmons AJ,Park R,Sterling NA,Jang MH,van Deursen JMA,Yen TJ,Cho SH,Kim S

Sat Jun 01 00:00:00 EDT 2019

Noncoding RNA Ginir functions as an oncogene by associating with centrosomal proteins.

PLoS biology

Panda S,Setia M,Kaur N,Shepal V,Arora V,Singh DK,Mondal A,Teli A,Tathode M,Gajula R,Padhy LC,Shiras A

Mon Oct 01 00:00:00 EDT 2018

Noncoding RNA Ginir functions as an oncogene by associating with centrosomal proteins.

PLoS biology

Panda S,Setia M,Kaur N,Shepal V,Arora V,Singh DK,Mondal A,Teli A,Tathode M,Gajula R,Padhy LC,Shiras A

Mon Oct 01 00:00:00 EDT 2018

Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.

Cancer cell

Zhang S,Chen Q,Liu Q,Li Y,Sun X,Hong L,Ji S,Liu C,Geng J,Zhang W,Lu Z,Yin ZY,Zeng Y,Lin KH,Wu Q,Li Q,Nakayama K,Nakayama KI,Deng X,Johnson RL,Zhu L,Gao D,Chen L,Zhou D

Mon May 08 00:00:00 EDT 2017

Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.

Cancer cell

Zhang S,Chen Q,Liu Q,Li Y,Sun X,Hong L,Ji S,Liu C,Geng J,Zhang W,Lu Z,Yin ZY,Zeng Y,Lin KH,Wu Q,Li Q,Nakayama K,Nakayama KI,Deng X,Johnson RL,Zhu L,Gao D,Chen L,Zhou D

Mon May 08 00:00:00 EDT 2017

Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50.

Journal of cell science

Kvainickas A,Orgaz AJ,Nägele H,Diedrich B,Heesom KJ,Dengjel J,Cullen PJ,Steinberg F

Sun Jan 15 00:00:00 EST 2017

Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50.

Journal of cell science

Kvainickas A,Orgaz AJ,Nägele H,Diedrich B,Heesom KJ,Dengjel J,Cullen PJ,Steinberg F

Sun Jan 15 00:00:00 EST 2017

Bioinformatics

Protein Aliases: centrosome marker; gamma tubulin; Gamma-1-tubulin; Gamma-2-tubulin; Gamma-tubulin complex component 1; GCP-1; Tubulin gamma-1 chain; Tubulin gamma-2 chain; tubulin, gamma 1; tubulin, gamma 2; tubulin, gamma polypeptide

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Gene Aliases: 1500010O08Rik; AI451582; AI503389; AI504772; CDCBM4; GCP-1; TUBG; TUBG1; TUBG2; TUBGCP1; Tubgl

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UniProt ID: (Human) P23258, (Dog) Q9GKK5, (Human) Q9NRH3, (Mouse) P83887, (Rat) P83888, (Mouse) Q8VCK3

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Entrez Gene ID: (Human) 7283, (Dog) 403695, (Human) 27175, (Mouse) 103733, (Rat) 252921, (Rat) 680991, (Mouse) 103768

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Function(s)

GTPase activity structural constituent of cytoskeleton protein binding GTP binding structural molecule activity nucleotide binding tubulin

Process(es)

G2/M transition of mitotic cell cycle meiotic spindle organization microtubule cytoskeleton organization microtubule nucleation cytoplasmic microtubule organization microtubule-based process mitotic spindle organization regulation of mitotic nuclear division protein polymerization metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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gamma Tubulin Polyclonal Antibody

gamma Tubulin Antibody (15176-1-AP) in ICC/IF

Product Details

15176-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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