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hnRNP A2B1 Antibody (MA1-34789) in WB
Western blot was performed using Anti-hnRNP A2B1 Monoclonal Antibody (DP3B3) (Product # MA1-34789) and a 37 and 38 kDa band corresponding to hnRNP A2B1 was observed across cell lines and tissues tested . Nuclear enriched extracts (30 µg lysate) of HEK-293 (Lane 1), HeLa (Lane 2), A-431 (Lane 3), MCF7 (Lane 4), RAW 264.7 (Lane 5), Mouse Thymus (Lane 6), Rat Thymus (Lane 7) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX). Resolved proteins were then transferred onto a Nitrocellulose membrane (Product # LC2... View More
Product Details
MA1-34789
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
DP3B3
Immunogen
Bacterially expressed His-hnRNPA2 fusion protein (Human).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1956047
Product Specific Information
MA1-34789 detects HNRNP A2/B1 from chicken, human samples.
Target Information
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp779B0244; FLJ22720; heterogeneous nuclear ribonucleoprotein A2; heterogeneous nuclear ribonucleoprotein B0a; heterogeneous nuclear ribonucleoprotein B0b; heterogeneous nuclear ribonucleoprotein B1; Heterogeneous nuclear ribonucleoproteins A2/B1; heterogeneous nuclear ribonucleoproteins A2/B1 {ECO:0000312|EMBL:BAF79676.1}; heterogenous nuclear ribonucleoprotein A2/B1; hnRNP A2 / hnRNP B1; hnRNP A2/B1; hnrnpa2b1 {ECO:0000250|UniProtKB:P22626}; nuclear ribonucleoprotein particle A2 protein; OTTHUMP00000202465; OTTHUMP00000202466
Gene Aliases: 9130414A06Rik; Hnrnp; hnrnp-A; HNRNPA2; HNRNPA2B1; HNRNPB1; HNRPA2; HNRPA2B1; HNRPB1; IBMPFD2; RNPA2; SNRPB1
UniProt ID: (Human) P22626, (Rat) A7VJC2, (Mouse) O88569
Entrez Gene ID: (Chicken) 420627, (Human) 3181, (Rat) 362361, (Mouse) 53379
negative regulation of transcription from RNA polymerase II promoter
mRNA processing
RNA splicing
male gonad development
lung development
negative regulation of mRNA splicing, via spliceosome
oligodendrocyte differentiation
RNA transport
response to mineralocorticoid
mRNA splicing, via spliceosome
mRNA export from nucleus
gene expression
primary miRNA processing
miRNA transport
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