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p38 MAPK gamma/delta Antibody (PA5-106253) in WB
Western blot analysis of p38 MAPK gamma/delta in extracts from various samples. Samples were incubated with p38 MAPK gamma/delta polyclonal antibody (Product # PA5-106253). Lane 1: Ec304 cells (heat-shock treatment), blocked with antigen-specific peptides; Lane 2: Ec304 cells (heat-shock treatment); Lane 3: Cos-7 cells (heat-shock treatment).
Product Details
PA5-106253
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MAPK12(Accession P53778), corresponding to amino acid residues N162-V212.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2817640
Product Specific Information
Antibody detects endogenous levels of total p38 gamma/delta.
Target Information
Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ERK-6; Exon skip; Extracellular signal-regulated kinase 6; MAP kinase 12; MAP kinase 13; MAP kinase p38 delta; MAP kinase p38 gamma; MAPK 12; MAPK 13; mitogen activated protein kinase 12; mitogen activated protein kinase 13; Mitogen-activated protein kinase 12; Mitogen-activated protein kinase 13; mitogen-activated protein kinase 3; Mitogen-activated protein kinase p38 delta; Mitogen-activated protein kinase p38 gamma; p38 delta MAP kinase; SAPK/Erk/kinase 4; stress activated protein kinase 3; Stress-activated protein kinase 3; Stress-activated protein kinase 4
Gene Aliases: AW123708; ERK-6; ERK3; ERK6; MAPK 12; MAPK 13; MAPK-13; MAPK12; MAPK13; p38delta; P38GAMMA; PRKM12; PRKM13; SAPK-3; SAPK3; SAPK4; Serk4
UniProt ID: (Human) P53778, (Human) O15264, (Mouse) O08911, (Mouse) Q9Z1B7
Entrez Gene ID: (Human) 6300, (Human) 5603, (Mouse) 29857, (Mouse) 26415
magnesium ion binding
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
non-receptor serine/threonine protein kinase
MAPK cascade
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage induced protein phosphorylation
cell cycle arrest
signal transduction
muscle organ development
positive regulation of peptidase activity
peptidyl-serine phosphorylation
myoblast differentiation
vascular endothelial growth factor receptor signaling pathway
positive regulation of muscle cell differentiation
response to stress
response to osmotic stress
cell cycle
positive regulation of interleukin-6 production
intracellular signal transduction
positive regulation of inflammatory response
protein phosphorylation
phosphorylation
negative regulation of cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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